Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling
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Characterization of the human sulfatase Sulf1 and its high affinity heparin/heparan sulfate interaction domainDirect detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88Functional consequences of the subdomain organization of the sulfsHSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cellsRecent Insights into Cell Surface Heparan Sulphate Proteoglycans and CancerHeparan sulfate and heparin interactions with proteinsHeparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myelomaHeparan sulfate biosynthesis enzymes in embryonic stem cell biologyArylsulfatase B improves locomotor function after mouse spinal cord injuryStructural basis of heparan sulfate-specific degradation by heparinase IIIWT1-dependent sulfatase expression maintains the normal glomerular filtration barrierActivation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regenerationSulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting FunctionsSulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinusCommon genetic variants and risk for HPV persistence and progression to cervical cancer.Regulation of intracellular signaling by extracellular glycan remodeling.High sodium diet converts renal proteoglycans into pro-inflammatory mediators in ratsMatrix regulators in neural stem cell functions.Glycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2.Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches.Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in miceHeparan sulfate proteoglycans.Loss of HSulf-1 expression enhances tumorigenicity by inhibiting Bim expression in ovarian cancer.Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines.Heparan sulfate differences in rheumatoid arthritis versus healthy seraHeparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant gliomaSulfatases are determinants of alveolar formation.Role of heparan sulfatases in ovarian and breast cancer.Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior.Proteoglycans and their roles in brain cancer.Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate developmentMethod development and analysis of free HS and HS in proteoglycans from pre- and postmenopausal women: evidence for biosynthetic pathway changes in sulfotransferase and sulfatase enzymes.Tissue-specificity of heparan sulfate biosynthetic machinery in cancer.Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling.Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neckSulf-2: an extracellular modulator of cell signaling and a cancer target candidate.
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P2860
Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@ast
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en-gb
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@nl
type
label
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@ast
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en-gb
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@nl
prefLabel
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@ast
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en-gb
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@nl
P2093
P921
P3181
P356
P1476
Sulf loss influences N-, 2-O-, ...... oblast growth factor signaling
@en
P2093
Marc-André Frese
Martina Balleininger
Thomas Dierks
William C Lamanna
P304
P3181
P356
10.1074/JBC.M802130200
P407
P577
2008-10-10T00:00:00Z