A human homolog of the S. cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region
about
HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndromeCore histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRAHIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionGenomic disorders on 22q11Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Replication-independent histone deposition by the HIR complex and Asf1.The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle.Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.A complex composed of tup1 and ssn6 represses transcription in vitro.Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethalityHip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation.HPC2 and ubinuclein define a novel family of histone chaperones conserved throughout eukaryotes.Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor IHP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.Structure and chromosomal localization of the RAE28/HPH1 gene, a human homologue of the polyhomeotic gene.The Saccharomyces cerevisiae histone chaperone Rtt106 mediates the cell cycle recruitment of SWI/SNF and RSC to the HIR-dependent histone genes.Genomic organization of TUPLE1/HIRA: a gene implicated in DiGeorge syndrome.Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth.Comparative mapping of the DiGeorge syndrome region in mouse shows inconsistent gene order and differential degree of gene conservation.Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients.Separation-of-function mutation in HPC2, a member of the HIR complex in S. cerevisiae, results in derepression of the histone genes but does not confer cryptic TATA phenotypes.The mitotic Clb cyclins are required to alleviate HIR-mediated repression of the yeast histone genes at the G1/S transition.Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complexDeletion mapping of 22q11 in CATCH22 syndrome: identification of a second critical region.Histone acetyltransferase 1 promotes homologous recombination in DNA repair by facilitating histone turnover.A Molecular Prospective for HIRA Complex Assembly and H3.3-Specific Histone Chaperone Function.The histone variant H3.3 claims its place in the crowded scene of epigenetics.The Schizosaccharomyces pombe HIRA-like protein Hip1 is required for the periodic expression of histone genes and contributes to the function of complex centromeresThe epigenetic regulation of embryonic myogenesis and adult muscle regeneration by histone methylation modificationHIRA, a conserved histone chaperone, plays an essential role in low-dose stress response via transcriptional stimulation in fission yeast.Subnuclear localization and mitotic phosphorylation of HIRA, the human homologue of Saccharomyces cerevisiae transcriptional regulators Hir1p/Hir2p.The fission yeast HIRA histone chaperone is required for promoter silencing and the suppression of cryptic antisense transcripts.How many breaks do we need to CATCH on 22q11?HIRA is essential for the development of gibel carp.Cloning and developmental expression analysis of chick Hira (Chira), a candidate gene for DiGeorge syndrome.High-resolution visualization of H3 variants during replication reveals their controlled recycling
P2860
Q24301030-E516175A-238B-445D-8CFB-21AEB960EB04Q24311544-3F56FFB1-12C6-4AA7-9239-33B1451BACB3Q24314765-58F86726-52C0-4E91-81FE-B612EBAC0D5BQ24329157-E428BBF0-9B73-4A69-AAE7-04B786261B9EQ24551005-32767E4F-2EDE-49C1-968C-806EFBB4228FQ24563977-15A72065-8327-42AA-9412-EE18BAA4E0E8Q26853406-ACD65987-BB47-4FCD-8021-4B42F5B2FD58Q27931963-AFE6D36E-2AD9-4A09-B2F4-07B9FF01817FQ27932671-F3E22D9B-E343-4211-9F3C-440B92F05369Q27934417-53C1763E-BDAF-468D-A140-20F4E3B2AC6BQ27936574-E5F576CF-EF5C-4823-B2B8-4C85B5445531Q27937273-9D2065BB-A0AF-4105-BECC-EC0220E01B48Q28586070-BC3D59AD-1222-4111-B82A-7AC725C962AFQ33232262-120EA699-CAEF-4AE0-A438-7E302D580D6FQ33410275-CF48652F-5BBA-4E13-93DA-A575DE0371D1Q33775938-A123C0DF-4823-415B-B57F-968AD11CBC05Q33828273-3A64C21C-AAA2-4B1D-B961-3C629539395BQ33910355-306D6064-EB07-4CA9-9448-D419F481D31AQ33941143-8352F609-BF85-4F6D-856A-5C48932EA4D9Q34413379-95EF9AD8-0FDA-4BFE-BE60-C19CAFF9E6D7Q34434637-CAB73210-1739-4A84-AE87-F77755B07EA9Q34447775-07118C5B-7FF9-4C97-8636-BF3FE8E70FE1Q35249478-0F3A840E-F486-4C4C-B033-E4FD86818AEFQ35269669-C1E73B6A-650F-468D-B455-44E16DB8999EQ35645277-9328B664-C3C7-41EF-BB13-1D76D28F6E27Q35878397-E9425E23-D0F1-477C-90A7-985B5DA33B78Q35882793-3C6A1E0D-04C1-498B-8315-3F8951FD9CD3Q36947806-C7A4BDAA-EC72-479A-B75E-BD23C84B3CA8Q39015896-9C91A5D4-8AF8-4464-B5C2-4F2A1997EF16Q39173837-2E78F084-BF93-4C33-82E1-FF5C192C6F00Q40815585-FA77D686-F59E-4CAE-AAE1-43B243874B4AQ41683062-31BC76C4-E5D4-4A35-95A2-8A1CF0295F5EQ41815758-D3EA0C4B-DD59-4888-BCB9-A65662D6B206Q41820207-2CA27A81-6184-47F6-994B-E0F273E416E3Q42138623-94D6CD69-DE3C-4145-9B14-AD603043775BQ42587476-1086AA4C-99F6-42DA-80DF-2B498F9714ABQ44370688-89C0BBA3-4EBB-4115-8E1B-96FF2A796E00Q48054324-B24AD097-A724-428B-B6DC-6C266311F4D5Q58793846-B3D359DA-F9DE-4DD7-A69D-5517AF3FE353
P2860
A human homolog of the S. cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A human homolog of the S. cere ...... eorge syndrome critical region
@ast
A human homolog of the S. cere ...... eorge syndrome critical region
@en
A human homolog of the S. cere ...... eorge syndrome critical region
@en-gb
A human homolog of the S. cere ...... eorge syndrome critical region
@nl
type
label
A human homolog of the S. cere ...... eorge syndrome critical region
@ast
A human homolog of the S. cere ...... eorge syndrome critical region
@en
A human homolog of the S. cere ...... eorge syndrome critical region
@en-gb
A human homolog of the S. cere ...... eorge syndrome critical region
@nl
prefLabel
A human homolog of the S. cere ...... eorge syndrome critical region
@ast
A human homolog of the S. cere ...... eorge syndrome critical region
@en
A human homolog of the S. cere ...... eorge syndrome critical region
@en-gb
A human homolog of the S. cere ...... eorge syndrome critical region
@nl
P2093
P356
P1476
A human homolog of the S. cere ...... eorge syndrome critical region
@en
P2093
M Bodescot
M Lipinski
P356
10.1093/HMG/4.5.791
P407
P577
1995-05-01T00:00:00Z