Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
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SIRT2 as a Therapeutic Target for Age-Related DisordersSIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylationCullin-RING ligases in regulation of autophagyRedox regulation of FoxO transcription factorsFoxO Transcription Factors and Regenerative Pathways in Diabetes MellitusThe controversial world of sirtuinsRegulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and agingC. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stressBetter Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and LifespanSIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivoSirtuin1 (Sirt1) promotes cortical bone formation by preventing β-catenin sequestration by FoxO transcription factors in osteoblast progenitors.WISP1: Clinical insights for a proliferative and restorative member of the CCN familySorting out functions of sirtuins in cancerA novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.Differential expression of sirtuins in the aging rat brainZebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7.SIRT1-dependent myoprotective effects of resveratrol on muscle injury induced by compression.Methylation by Set9 modulates FoxO3 stability and transcriptional activity.Sirtuin biology and relevance to diabetes treatment.Acetylation-dependent function of human single-stranded DNA binding protein 1.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadeNovel directions for diabetes mellitus drug discoveryFoxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex.Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling.WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1Coordination of autophagy with other cellular activitiesSite-specific acetylation of the proteasome activator REGγ directs its heptameric structure and functions.Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3aForkhead transcription factors: new considerations for alzheimer's disease and dementia.SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation.The Roles of SIRT1 in Cancer.Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression.The emerging and diverse roles of sirtuins in cancer: a clinical perspective.SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth.Regulation of FOXO3 by phosphorylation and methylation in hepatitis C virus infection and alcohol exposure.Using the ubiquitin-modified proteome to monitor protein homeostasis function.The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.Epigenetic silencing of ARRDC3 expression in basal-like breast cancer cellsAntiaging properties of a grape-derived antioxidant are regulated by mitochondrial balance of fusion and fission leading to mitophagy triggered by a signaling network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN.
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Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@ast
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en-gb
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@nl
type
label
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@ast
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en-gb
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@nl
prefLabel
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@ast
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en-gb
Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@nl
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P2860
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Deacetylation of FOXO3 by SIRT ...... ubiquitination and degradation
@en
P2093
P2860
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P304
P3181
P356
10.1038/ONC.2011.347
P407
P577
2012-03-22T00:00:00Z
P6179
1004622300