Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases
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Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif-bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbetaResidue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alphaMyotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphateProtein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylationTYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1BRegulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblastsSKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcriptionReceptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor functionSelective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatasePhosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationProtein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptorsRegulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTPProtein tyrosine phosphatase 1B participates in the down-regulation of erythropoietin receptor signallingT cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in miceDynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells.Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domainsPositive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphataseH2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress responseThe receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1Reactivation of oxidized PTP1B and PTEN by thioredoxin 1Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase TThe role of protein-tyrosine phosphatase 1B in integrin signalingControl of vesicle fusion by a tyrosine phosphataseIdentification of substrates of human protein-tyrosine phosphatase PTPN22Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cellsThe SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificitiesLoss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motilityThe tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingInsights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variantsSubstrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrateIdentification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cellsProtein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo.Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migrationPTP1B regulates Eph receptor function and traffickingCalcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling eventsRegulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase
P2860
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P2860
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Development of "substrate-trap ...... protein tyrosine phosphatases
@ast
Development of "substrate-trap ...... protein tyrosine phosphatases
@en
Development of "substrate-trap ...... protein tyrosine phosphatases
@en-gb
Development of "substrate-trap ...... protein tyrosine phosphatases
@nl
type
label
Development of "substrate-trap ...... protein tyrosine phosphatases
@ast
Development of "substrate-trap ...... protein tyrosine phosphatases
@en
Development of "substrate-trap ...... protein tyrosine phosphatases
@en-gb
Development of "substrate-trap ...... protein tyrosine phosphatases
@nl
prefLabel
Development of "substrate-trap ...... protein tyrosine phosphatases
@ast
Development of "substrate-trap ...... protein tyrosine phosphatases
@en
Development of "substrate-trap ...... protein tyrosine phosphatases
@en-gb
Development of "substrate-trap ...... protein tyrosine phosphatases
@nl
P2093
P2860
P3181
P356
P1476
Development of "substrate-trap ...... protein tyrosine phosphatases
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.94.5.1680
P407
P50
P577
1997-03-04T00:00:00Z