Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
about
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiencyCloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cellsJanus kinases in immune cell signalingIdentification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptorMissense mutation in exon 7 of the common gamma chain gene causes a moderate form of X-linked combined immunodeficiencyDefective human interleukin 2 receptor gamma chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cellsDifferent interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferationThree residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSFUtilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinaseFemale germ line mosaicism as the origin of a unique IL-2 receptor gamma-chain mutation causing X-linked severe combined immunodeficiencySynergistic action of stem-cell factor and interleukin-7 in a human immature T-cell lineRegulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteinsFunctional cleavage of the common cytokine receptor gamma chain (gammac) by calpainDevelopment of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) miceTwo mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiencyRegulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7Bladder carcinomas and normal urothelium universally express gp200-MR6, a molecule functionally associated with the interleukin 4 receptor (CD 124)Targeting Homeostatic T Cell Proliferation to Control Beta-Cell AutoimmunityThe shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapyCo-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunctionFunctional analysis of the human interleukin 2 receptor gamma chain gene promoterImpairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient miceDistinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversityHeteromerization of the c Chain with the Interleukin-9 Receptor Subunit Leads to STAT Activation and Prevention of ApoptosisA molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease.Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9.Interleukin-7, a new cytokine targeting the mouse hypothalamic arcuate nucleus: role in body weight and food intake regulation.The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexesCloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptorDevelopment of a recombinant interleukin-4-Pseudomonas exotoxin for therapy of glioblastoma.Soluble cytokine receptors: basic immunology and clinical applications.Interleukin-2 signaling and inherited immunodeficiency.Human lymphoid development in the absence of common γ-chain receptor signaling.A novel functional rabbit IL-7 isoform.The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cellsInterleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.Interleukin-7 receptor-α gene mutations are not detected in adult T-cell acute lymphoblastic leukemia.
P2860
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P2860
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@ast
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en-gb
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@nl
type
label
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@ast
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en-gb
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@nl
prefLabel
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@ast
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en-gb
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@nl
P2093
P921
P3181
P356
P1433
P1476
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
@en
P2093
S F Ziegler
S M Russell
W J Leonard
Y Nakamura
P304
P3181
P356
10.1126/SCIENCE.8266077
P407
P577
1993-12-17T00:00:00Z