Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
about
Influence of cell detachment on the respiration rate of tumor and endothelial cellsReductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxiaMetabolic control of the epigenome in systemic Lupus erythematosus.Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cellsInhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levelsThe Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanismInhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin.The effect of acyclic retinoid on the metabolomic profiles of hepatocytes and hepatocellular carcinoma cells.LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small-cell lung cancer (NSCLC) cells.Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants.Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathwaysGlucose oxidation modulates anoikis and tumor metastasis.Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment.Metabolism of [U-13 C]glucose in human brain tumors in vivoIsotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells.Expanding the concepts and tools of metabolic engineering to elucidate cancer metabolism.Reductive carboxylation supports redox homeostasis during anchorage-independent growth.IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolismEnzymatic passaging of human embryonic stem cells alters central carbon metabolism and glycan abundanceManganese superoxide dismutase promotes anoikis resistance and tumor metastasisThe ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux.Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster.Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells.Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress.Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line.Mapping cancer cell metabolism with(13)C flux analysis: Recent progress and future challenges.Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrinsRegulation of pyruvate metabolism in metabolic-related diseases.Mitochondria as biosynthetic factories for cancer proliferation.The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents.Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape.Differential impact of flavonoids on redox modulation, bioenergetics and cell signalling in normal and tumor cells: a comprehensive review.Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer.Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration.The antineoplastic effect of carnosine is accompanied by induction of PDK4 and can be mimicked by L-histidine.LKB1 promotes metabolic flexibility in response to energy stress.Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT).
P2860
Q28485383-90779A32-46CE-444B-9705-572955C87BB6Q29616650-D9B7AA42-0F29-4539-A47E-8CA3554F1C93Q33664849-38A99028-4500-4DE5-8000-4FC99EDA58BEQ33705623-9D1CD920-52F9-45DC-8683-1FB14C73AAF4Q34315365-67748521-BE1B-474B-BF31-A9EB2645B07CQ34332654-03419A7F-C919-4E15-A82C-BD7BE4978EC6Q34388048-0CE5A5E5-0B36-482E-A5FD-326D17460B39Q35077773-F3E4FF56-5D55-4629-ACA8-FD49A73BAAEEQ35801173-AE26C791-36ED-453D-A03F-C4AC127B4C1FQ35804053-02D63659-9C6A-44EA-AF65-C472B7E5E7CDQ35879138-2D98FC25-D0E0-4959-B390-C9DA00CBC32FQ35919019-88DF8727-88EC-40C2-8CA0-309C25F43AA7Q35943920-DF1E0021-3D99-4E24-99CD-3B6C8BF1BFB1Q35955337-70C1E066-E04A-4955-B200-709052B137A9Q36120642-DF7C036C-65D3-45ED-BCDF-3669AED94226Q36503881-FE4A880D-ADA8-4CF8-82CC-28ECB6D94D15Q36650394-F728C1A5-E1D7-42F1-A496-7F02B4335F52Q36883158-D8C0D635-5EA5-4C45-A1E8-B2452F3177FEQ36948088-2721AC74-6DAB-4AC9-BA37-E1E085BAC67BQ36948091-16CFC67D-3770-4E49-B803-BE927FC2CBAFQ37073610-49A12C8D-3692-4415-B1A0-66C49577E343Q37125226-AC60321D-959F-407E-A9B1-9993F371CF8DQ37594446-AC42FA90-E73F-41DC-96EB-B07C26AFDC89Q37604718-15730192-C167-4874-9021-08275FF85C56Q37649672-1A62D1A7-07EB-4AED-B651-97BEEEE0E54FQ37743312-B5A73502-B27F-47DF-9CDB-FB2A3CE3E71DQ38130258-70AB2414-D474-44C4-9B65-E777327A8FE3Q38138161-E48774DA-6AEB-471F-B93E-1CA3FA1BD48AQ38161453-6DDD6C1F-E521-424A-816F-5F0C5FB5F775Q38332527-54CEA79D-C09A-41C2-BDC7-0E99A4A46682Q38418672-9EECAC39-246C-416A-AEC1-140C590EDC21Q38600506-582A8C45-7900-44D7-A3AE-AC97ACA64E21Q38616035-B96DCFED-ED04-44CA-8828-DD08251FF6E1Q38686612-286844C4-F993-4070-B627-4CEBDFAE3824Q38762901-4DE69B77-B53C-4B7C-991D-9E97F14DCC97Q38816034-CFF728D4-AB2C-4405-A470-EBED89A1A831Q39036650-440B6AA4-686D-42ED-B2AA-4F8DA2DDA6F2Q39051999-513AA8A9-4273-4669-9EC2-5769F1EC57E1Q39117748-EEF13AB4-AC28-480A-8B73-7DD0E5CE258AQ39265553-A87F4B4C-E9F7-4DE8-A200-301E668464DC
P2860
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@ast
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en-gb
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@nl
type
label
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@ast
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en-gb
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@nl
prefLabel
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@ast
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en-gb
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@nl
P2093
P2860
P3181
P356
P1433
P1476
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
@en
P2093
Alexandra R Grassian
Christian M Metallo
Gregory Stephanopoulos
Joan S Brugge
Jonathan L Coloff
P2860
P304
P3181
P356
10.1101/GAD.16771811
P407
P577
2011-08-15T00:00:00Z