Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells - Wikidata - awgldk - TriplyDB

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

http://www.wikidata.org/entity/Q24324074

about

Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation Mammary Development and Breast Cancer: A Wnt Perspective EGFR signaling in renal fibrosis Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin EGF receptor ligands: recent advances Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis Dual blockade of the EGFR and COX-2 pathways: a phase II trial of cetuximab and celecoxib in patients with chemotherapy refractory metastatic colorectal cancer.Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.Convergence between Wnt-β-catenin and EGFR signaling in cancer.Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.A systems view of epithelial-mesenchymal transition signaling states.Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling.Cell-autonomous, myristyl-independent activity of the Drosophila Wnt/Wingless antagonist Naked cuticle (Nkd).A monoclonal antibody produced against Naked2.Structural studies of human Naked2: a biologically active intrinsically unstructured protein.Epidermal growth factor cytoplasmic domain affects ErbB protein degradation by the lysosomal and ubiquitin-proteasome pathway in human cancer cells.TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth.Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer Transformation of polarized epithelial cells by apical mistrafficking of epiregulin The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.ERBBs in the gastrointestinal tract: recent progress and new perspectives.Taking the scenic route: biosynthetic traffic to the plasma membrane in polarized epithelial cells Clathrin and AP1B: key roles in basolateral trafficking through trans-endosomal routes NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma Directional Fluid Transport across Organ-Blood Barriers: Physiology and Cell Biology.Identification of a novel mono-leucine basolateral sorting motif within the cytoplasmic domain of amphiregulin.Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.The C-terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice.Recycling of cell surface pro-transforming growth factor-{alpha} regulates epidermal growth factor receptor activation.Nkd2 promotes the differentiation of dental follicle stem/progenitor cells into osteoblasts

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P2860

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

http://www.wikidata.org/entity/Q24324074

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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type

label

Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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Proceedings of the National Academy of Sciences of the United States of America

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Myristoylated Naked2 escorts t ...... of polarized epithelial cells

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P2093

Cunxi Li

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Jeffrey L Franklin

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Ramona Graves-Deal

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Robert J Coffey

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W Gray Jerome

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Zheng Cao

http://www.w3.org/2001/XMLSchema#string

P2860

Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids

Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

The biology and enzymology of protein N-myristoylation

Naked cuticle targets dishevelled to antagonize Wnt signal transduction

Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching

naked cuticle encodes an inducible antagonist of Wnt signalling.

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3614379

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10.1073/PNAS.0401294101

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15

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101

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2004-04-13T00:00:00Z

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8638004

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15064403

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P921

positive regulation of protein localization to plasma membrane

NKD inhibitor of WNT signaling pathway 2

Transforming growth factor alpha

P932

397424

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