Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5
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Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerizationCa2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sitesSolution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5Calmodulin regulation (calmodulation) of voltage-gated calcium channelsTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsCrystallographic basis for calcium regulation of sodium channelsThe C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rateCrystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and CalmodulinThe number and location of EF hand motifs dictates the calcium dependence of polycystin-2 functionStructure of the Small Dictyostelium discoideum Myosin Light Chain MlcB Provides Insights into MyoB IQ Motif RecognitionPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasSodium channel carboxyl-terminal residue regulates fast inactivation.Regulation of the NaV1.5 cytoplasmic domain by calmodulinRelating form and function of EF-hand calcium binding proteins.Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.Mechanisms of a human skeletal myotonia produced by mutation in the C-terminus of NaV1.4: is Ca2+ regulation defective?Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels.Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.Computer aided identification of sodium channel blockers in the clinical treatment of epilepsy using molecular docking tools.Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation.Survey of the year 2009: applications of isothermal titration calorimetry.NaChBac: the long lost sodium channel ancestorBiology of cardiac sodium channel Nav1.5 expression.Seeing the forest through the trees: towards a unified view on physiological calcium regulation of voltage-gated sodium channels.Structural diversity of calmodulin binding to its target sites.Determinants of myocardial conduction velocity: implications for arrhythmogenesis.Voltage-gated sodium channels in the mammalian heart.Current view on regulation of voltage-gated sodium channels by calcium and auxiliary proteins.Dynamic switching of calmodulin interactions underlies Ca2+ regulation of CaV1.3 channels.Conservation of Ca2+/calmodulin regulation across Na and Ca2+ channels.Thermodynamic linkage between calmodulin domains binding calcium and contiguous sites in the C-terminal tail of Ca(V)1.2.Intracellular calcium attenuates late current conducted by mutant human cardiac sodium channels.Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.Sodium channel traffic on the cardiac microtubule highway.Mechanisms and models of cardiac sodium channel inactivation.Differential calcium sensitivity in NaV 1.5 mixed syndrome mutants.The efficacy of Ranolazine on E1784K is altered by temperature and calcium.Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations.A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.
P2860
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P2860
Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
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2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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type
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
@en
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
@en-gb
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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altLabel
Solution NMR Structure of the ...... Cardiac Sodium Channel NaV1.5
@en
prefLabel
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
@ast
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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Solution NMR structure of the ...... cardiac sodium channel NaV1.5
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P2093
P2860
P921
P356
P1476
Solution NMR structure of the ...... cardiac sodium channel NaV1.5
@en
P2093
Benjamin Chagot
Franck Potet
Jeffrey R Balser
Walter J Chazin
P2860
P304
P356
10.1074/JBC.M807747200
P407
P577
2009-03-06T00:00:00Z