Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
about
Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephalyFunctional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoidsA novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancerForkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functionsIdentification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cellsTumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamilyThe estrogen-responsive B box protein: a novel regulator of keratinocyte differentiationA zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcriptionNRIP, a novel nuclear receptor interaction protein, enhances the transcriptional activity of nuclear receptorsRole for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II functionCLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregationThe histone methyltransferase, NSD2, enhances androgen receptor-mediated transcriptionThe estrogen-responsive B box protein is a novel regulator of the retinoid signalThe structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylationActivating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteinsDomain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation.Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator.Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptorsMetastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulatorNSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypesRegulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancerSUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR.The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.The yeast protein Xtc1 functions as a direct transcriptional repressor.Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsMICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functionsThe role of NUP98 gene fusions in hematologic malignancyThe transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domainsNizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motifCharacterization of zinc finger protein 496 that interacts with Jumonji/Jarid2Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouseNSD1 is essential for early post-implantation development and has a catalytically active SET domainCore LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors.The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.Genetic syndromes associated with overgrowth in childhood.Role of the essential yeast protein PSU1 in p6anscriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors.
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P2860
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Two distinct nuclear receptor ...... corepressors and coactivators
@ast
Two distinct nuclear receptor ...... corepressors and coactivators
@en
Two distinct nuclear receptor ...... corepressors and coactivators
@en-gb
Two distinct nuclear receptor ...... corepressors and coactivators
@nl
type
label
Two distinct nuclear receptor ...... corepressors and coactivators
@ast
Two distinct nuclear receptor ...... corepressors and coactivators
@en
Two distinct nuclear receptor ...... corepressors and coactivators
@en-gb
Two distinct nuclear receptor ...... corepressors and coactivators
@nl
prefLabel
Two distinct nuclear receptor ...... corepressors and coactivators
@ast
Two distinct nuclear receptor ...... corepressors and coactivators
@en
Two distinct nuclear receptor ...... corepressors and coactivators
@en-gb
Two distinct nuclear receptor ...... corepressors and coactivators
@nl
P2093
P2860
P921
P356
P1433
P1476
Two distinct nuclear receptor ...... corepressors and coactivators
@en
P2093
E vom Baur
J L Vonesch
J M Garnier
P2860
P304
P356
10.1093/EMBOJ/17.12.3398
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P577
1998-06-01T00:00:00Z