Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes
about
Protein prenyltransferasesAIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteinsp619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteinsPrenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cellsPrenylation of Rab8 GTPase by type I and type II geranylgeranyl transferasesRhoGDI-binding-defective mutant of Cdc42Hs targets to membranes and activates filopodia formation but does not cycle with the cytosol of mammalian cellsThe Rab GTPase familyFunctional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complexRab9 GTPase regulates late endosome size and requires effector interaction for its stabilityStructure of mammalian protein geranylgeranyltransferase type-IStructures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylationThe putative "switch 2" domain of the Ras-related GTPase, Rab1B, plays an essential role in the interaction with Rab escort proteinRapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models.Recycling Endosomes and Viral InfectionEndoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavageGTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport.Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p.Genome Analysis of Osteosarcoma Progression Samples Identifies FGFR1 Overexpression as a Potential Treatment Target and CHM as a Candidate Tumor Suppressor GeneRole of Rab GTPases in membrane traffic and cell physiologyA novel statin-mediated "prenylation block-and-release" assay provides insight into the membrane targeting mechanisms of small GTPases.Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patientsPostprenylation CAAX processing is required for proper localization of Ras but not Rho GTPasesAre Rab proteins the link between Golgi organization and membrane trafficking?Silencing of the CHM gene alters phagocytic and secretory pathways in the retinal pigment epitheliumRab proteins implicated in lipid storage and mobilization.AAV-mediated gene therapy for choroideremia: preclinical studies in personalized models.Shuttling and translocation of heterotrimeric G proteins and Ras.Rab GTPase prenylation hierarchy and its potential role in choroideremia diseaseAnalysis of the small GTPase gene superfamily of Arabidopsis.Membrane targeting of Rab GTPases is influenced by the prenylation motifCOPI recruitment is modulated by a Rab1b-dependent mechanismRab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities.Molecular basis for Rab prenylationRab proteins and Rab-associated proteins: major actors in the mechanism of protein-trafficking disorders.The functional effect of pathogenic mutations in Rab escort protein 1.Amino- and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins.Inhibition of early endosome fusion by Rab5-binding defective Ras interference 1 mutants.Single GDP-dissociation Inhibitor Protein regulates endocytic and secretory pathways in Leishmania.The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif.Clinical and genetic studies in a family with a new splice-site mutation in the choroideremia gene.
P2860
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P2860
Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Rab escort protein-1 is a mult ...... eins to their target membranes
@ast
Rab escort protein-1 is a mult ...... eins to their target membranes
@en
Rab escort protein-1 is a mult ...... eins to their target membranes
@en-gb
Rab escort protein-1 is a mult ...... eins to their target membranes
@nl
type
label
Rab escort protein-1 is a mult ...... eins to their target membranes
@ast
Rab escort protein-1 is a mult ...... eins to their target membranes
@en
Rab escort protein-1 is a mult ...... eins to their target membranes
@en-gb
Rab escort protein-1 is a mult ...... eins to their target membranes
@nl
prefLabel
Rab escort protein-1 is a mult ...... eins to their target membranes
@ast
Rab escort protein-1 is a mult ...... eins to their target membranes
@en
Rab escort protein-1 is a mult ...... eins to their target membranes
@en-gb
Rab escort protein-1 is a mult ...... eins to their target membranes
@nl
P2093
P2860
P3181
P1433
P1476
Rab escort protein-1 is a mult ...... eins to their target membranes
@en
P2093
H Horiuchi
K Alexandrov
M C Seabra
O Steele-Mortimer
P2860
P304
P3181
P407
P577
1994-11-15T00:00:00Z