A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets
about
Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variantsTULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast functionTULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of SykAnti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.Attempting to rewrite History: challenges with the analysis of histidine-phosphorylated peptides.Protection from systemic Candida albicans infection by inactivation of the Sts phosphatasesRegulation and function of syk tyrosine kinase in mast cell signaling and beyond.Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach.Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulationUBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases.TULA-family proteins: a new class of cellular regulators.Cbl proteins in platelet activation.The extended human PTPome: a growing tyrosine phosphatase family.Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition.Increased Resistance to Intradermal Francisella tularensis LVS Infection by Inactivation of the Sts Phosphatases.Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo.Advances in development of new tools for the study of phosphohistidine.Histidine kinases and the missing phosphoproteome from prokaryotes to eukaryotes.Suppressor of TCR signaling-2 (STS-2) suppresses arthritis development in mice.UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets.The Extended Family of Protein Tyrosine Phosphatases.Platelet Signaling Pathways and New Inhibitors.Trypsin causes platelet activation independently of known protease-activated receptors.Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy.
P2860
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P2860
A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets
description
2010 nî lūn-bûn
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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@ast
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en-gb
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@nl
type
label
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@ast
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en-gb
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@nl
prefLabel
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@ast
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en-gb
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@nl
P2093
P2860
P1433
P1476
A novel histidine tyrosine pho ...... es GPVI signaling in platelets
@en
P2093
Alexander Y Tsygankov
Carol A Dangelmaier
Dafydd H Thomas
James L Daniel
Nick Carpino
Satya P Kunapuli
Tiffanny N Newman
Todd M Getz
P2860
P304
P356
10.1182/BLOOD-2010-02-268136
P407
P577
2010-10-07T00:00:00Z