Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast
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Spatiotemporal Regulation of Nuclear Transport Machinery and Microtubule OrganizationMto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-AAlp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.Optimization of the analogue-sensitive Cdc2/Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysisRole of Ran-regulated nuclear-cytoplasmic trafficking of pVHL in the regulation of microtubular stability-mediated HIF-1α in hypoxic cardiomyocytesLocalized accumulation of tubulin during semi-open mitosis in the Caenorhabditis elegans embryo.Spindle pole body components are reorganized during fission yeast meiosisThe internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.Space shuttling in the cell: nucleocytoplasmic transport and microtubule organization during the cell cycle.Differentiating the roles of microtubule-associated proteins at meiotic kinetochores during chromosome segregation.Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast.Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.
P2860
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P2860
Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@ast
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en-gb
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@nl
type
label
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@ast
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en-gb
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@nl
prefLabel
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@ast
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en-gb
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@nl
P2093
P2860
P356
P1433
P1476
Nucleocytoplasmic transport of ...... ule formation in fission yeast
@en
P2093
Masamitsu Sato
Masayuki Yamamoto
Naoyuki Okada
Takashi Toda
P2860
P304
P356
10.1038/EMBOR.2009.158
P407
P577
2009-10-01T00:00:00Z