Thyroid hormone receptor mutants that cause resistance to thyroid hormone. Evidence for receptor competition for DNA sequences in target genes

Thyroid hormone receptor mutants that cause resistance to thyroid hormone. Evidence for receptor competition for DNA sequences in target genes

Item
http://www.wikidata.org/entity/Q24336959
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptorNuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormoneThyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding beta-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways.Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potencyLiganded thyroid hormone receptor inhibits phorbol 12-O-tetradecanoate-13-acetate-induced enhancer activity via firefly luciferase cDNA.Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta geneThyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC)Identical mutations in unrelated families with generalized resistance to thyroid hormone occur in cytosine-guanine-rich areas of the thyroid hormone receptor beta gene. Analysis of 15 familiesCell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptorsThe erbA oncogene represses the actions of both retinoid X and retinoid A receptors but does so by distinct mechanisms.Mutations of CpG dinucleotides located in the triiodothyronine (T3)-binding domain of the thyroid hormone receptor (TR) beta gene that appears to be devoid of natural mutations may not be detected because they are unlikely to produce the clinical phPositive and negative modulation of Jun action by thyroid hormone receptor at a unique AP1 site.A potential role of activated NF-kappa B in the pathogenesis of euthyroid sick syndromeThyroid-hormone-dependent negative regulation of thyrotropin beta gene by thyroid hormone receptors: study with a new experimental system using CV1 cells.A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone.Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors.A clinician's guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms.
P2860

Thyroid hormone receptor mutants that cause resistance to thyroid hormone. Evidence for receptor competition for DNA sequences in target genes

Item
http://www.wikidata.org/entity/Q24336959
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@ast
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en-gb
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@nl
type
label
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@ast
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en-gb
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@nl
prefLabel
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@ast
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en-gb
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@nl
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P921
P1433
P1476
Thyroid hormone receptor mutan ...... DNA sequences in target genes
@en
P2093
P304
P31
P407
P433
P478
P577
P698
P921