DNA wrapping and distortion by an oligomeric homeodomain protein
about
Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasionThe proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturationPRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factorHhex Is Necessary for the Hepatic Differentiation of Mouse ES Cells and Acts via Vegf Signaling.CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation.PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin.DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers.Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival.
P2860
Q26766056-8F8464DE-C755-413E-801C-D925C767F80BQ28482476-A1F3DCF3-A349-4FC8-9967-FFA937F96990Q33826204-9A6C685B-67C2-400C-B080-B179F8718B09Q34522881-BE4412FA-553C-470D-A033-00EC916FD35BQ35897580-7887B642-6643-4387-8B78-AACB15279AD2Q38992187-51F09885-0E61-4D6C-8804-05366142A0D5Q39062393-247B6789-1ACF-4019-BD97-0C9C40087F9DQ41350960-28BC1760-49A2-4CE1-BF50-416DC67B8198Q41881515-0333354B-78B5-49A8-9A6E-09FC82D4AC5C
P2860
DNA wrapping and distortion by an oligomeric homeodomain protein
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
DNA wrapping and distortion by an oligomeric homeodomain protein
@ast
DNA wrapping and distortion by an oligomeric homeodomain protein
@en
DNA wrapping and distortion by an oligomeric homeodomain protein
@en-gb
DNA wrapping and distortion by an oligomeric homeodomain protein
@nl
type
label
DNA wrapping and distortion by an oligomeric homeodomain protein
@ast
DNA wrapping and distortion by an oligomeric homeodomain protein
@en
DNA wrapping and distortion by an oligomeric homeodomain protein
@en-gb
DNA wrapping and distortion by an oligomeric homeodomain protein
@nl
prefLabel
DNA wrapping and distortion by an oligomeric homeodomain protein
@ast
DNA wrapping and distortion by an oligomeric homeodomain protein
@en
DNA wrapping and distortion by an oligomeric homeodomain protein
@en-gb
DNA wrapping and distortion by an oligomeric homeodomain protein
@nl
P2093
P50
P3181
P1476
DNA wrapping and distortion by an oligomeric homeodomain protein
@en
P2093
Hannah Williams
Kevin Gaston
Padma-Sheela Jayaraman
P3181
P356
10.1016/J.JMB.2008.08.004
P407
P577
2008-08-07T00:00:00Z