The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
about
Evaluation of protein biomarkers of prostate cancer aggressivenessGaleterone for the treatment of advanced prostate cancer: the evidence to dateTouch and go: nuclear proteolysis in the regulation of metabolic genes and cancerDysregulation of ubiquitin ligases in cancerGenome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulationTargeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour developmentThe von hippel-lindau protein suppresses androgen receptor activity.JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cellsNeuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.Copy number alteration burden predicts prostate cancer relapseInvestigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancerMolecular pathways and targets in prostate cancerSeven In Absentia Homolog 2 (SIAH2) downregulation is associated with tamoxifen resistance in MCF-7 breast cancer cells.SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination.Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants.Roles of ubiquitination and SUMOylation on prostate cancer: mechanisms and clinical implications.MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells.The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer.Alterations in ubiquitin ligase Siah-2 and its corepressor N-CoR after P-MAPA immunotherapy and anti-androgen therapy: new therapeutic opportunities for non-muscle invasive bladder cancer.The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer CellsComputational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines.The Deubiquitinating Enzyme USP7 Regulates Androgen Receptor Activity by Modulating Its Binding to Chromatin.Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.SIAH2 protein expression in breast cancer is inversely related with ER status and outcome to tamoxifen therapyThe ubiquitin ligase Siah2 is revealed as an accomplice of the androgen receptor in castration resistant prostate cancer.BAP18 coactivates androgen receptor action and promotes prostate cancer progression.Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cellsDeacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity.Aldo-Keto Reductase AKR1C1-AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy.RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells.Maintaining and reprogramming genomic androgen receptor activity in prostate cancer.Implications of ubiquitin ligases in castration-resistant prostate cancer.SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2.The expression of glucocorticoid receptor is negatively regulated by active androgen receptor signaling in prostate tumors.Near-infrared fluorescence imaging of cancer mediated by tumor hypoxia and HIF1α/OATPs signaling axis
P2860
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P2860
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@ast
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en-gb
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@nl
type
label
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@ast
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en-gb
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@nl
prefLabel
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@ast
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en-gb
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@nl
P2093
P2860
P3181
P1433
P1476
The E3 ubiquitin ligase Siah2 ...... eptor transcriptional activity
@en
P2093
Giuseppina Claps
Jianfei Qi
Ladan Fazil
Ladan Fazli
Leland W K Chung
Manisha Tripathi
Martin Gleave
Natasha Sahgal
Neil Bhowmick
Rajeev Mishra
P2860
P304
P3181
P356
10.1016/J.CCR.2013.02.016
P407
P577
2013-03-18T00:00:00Z