Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3
about
Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the beta-adrenergic signal in the myocardiumCross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingcGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac MyocytesKnockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury.PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge.Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension.Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.Advances in targeting cyclic nucleotide phosphodiesterasescGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages.Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency.Nitric oxide decreases the permselectivity of the paracellular pathway in thick ascending limbsAtrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway.Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling.Role of reactive oxygen and nitrogen species in the vascular responses to inflammation.Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway.Endothelial actions of atrial and B-type natriuretic peptidesThe heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansionEpac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection.Soluble guanylyl cyclase contributes to ventilator-induced lung injury in miceInhibition of endothelial nitric oxide synthase decreases breast cancer cell MDA-MB-231 adhesion to intact microvessels under physiological flows.Myosin light chain kinase signaling in endothelial barrier dysfunction.Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis.The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels.GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP.Increased microvascular permeability in mice lacking Epac1 (Rapgef3).Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.Regulation of endothelial barrier function by cyclic nucleotides: the role of phosphodiesterases.Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system.Regulation of cardiovascular TRP channel functions along the NO-cGMP-PKG axis.Endothelial cell's biomechanical properties are regulated by invasive cancer cells.Cyclic nucleotide phosphodiesterases (PDEs): coincidence detectors acting to spatially and temporally integrate cyclic nucleotide and non-cyclic nucleotide signals.Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST).Molecular Physiology of Membrane Guanylyl Cyclase Receptors.Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathwaysReal-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6.Phosphodiesterase 4 inhibition attenuates atrial natriuretic peptide-induced vascular hyperpermeability and loss of plasma volume.Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice.
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P2860
Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Differential regulation of end ...... via phosphodiesterases 2 and 3
@ast
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en-gb
Differential regulation of end ...... via phosphodiesterases 2 and 3
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type
label
Differential regulation of end ...... via phosphodiesterases 2 and 3
@ast
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en-gb
Differential regulation of end ...... via phosphodiesterases 2 and 3
@nl
prefLabel
Differential regulation of end ...... via phosphodiesterases 2 and 3
@ast
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en
Differential regulation of end ...... via phosphodiesterases 2 and 3
@en-gb
Differential regulation of end ...... via phosphodiesterases 2 and 3
@nl
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Differential regulation of end ...... via phosphodiesterases 2 and 3
@en
P2093
James Surapisitchat
Joseph A Beavo
Kye-Im Jeon
P3181
P356
10.1161/CIRCRESAHA.107.154229
P407
P577
2007-10-12T00:00:00Z