Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
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Cathepsin S signals via PAR2 and generates a novel tethered ligand receptor agonistPlasmatic level of neurosin predicts outcome of mild cognitive impairment.Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distributionRole of the first extracellular loop in the functional activation of CCR2. The first extracellular loop contains distinct domains necessary for both agonist binding and transmembrane signalingThrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathwayCellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substratesProteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytesArginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretionA novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalizationCloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissuePlasminogen activator inhibitor-1 and vitronectin promote the cellular clearance of thrombin by low density lipoprotein receptor-related proteins 1 and 2Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tailsThe protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascadeHuman platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteinsEpstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptorsALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sortingThe phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombinRas activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase CProteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRsPombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signalingThrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activationTyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-proteinPleckstrin inhibits phosphoinositide hydrolysis initiated by G-protein-coupled and growth factor receptors. A role for pleckstrin's PH domainsBradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zetaCloning and characterization of human protease-activated receptor 4Thrombin receptor overexpression in malignant and physiological invasion processesG alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase CMolecular cloning, expression and potential functions of the human proteinase-activated receptor-2Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytesG proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human plateletsDown-regulation of protease-activated receptor-1 is regulated by sorting nexin 1Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.Characterization of a functional thrombin receptor. Issues and opportunitiesMast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblastsThe proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cellsEvidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytesProtease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
P2860
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P2860
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Molecular cloning of a functio ...... chanism of receptor activation
@ast
Molecular cloning of a functio ...... chanism of receptor activation
@en
Molecular cloning of a functio ...... chanism of receptor activation
@en-gb
Molecular cloning of a functio ...... chanism of receptor activation
@nl
type
label
Molecular cloning of a functio ...... chanism of receptor activation
@ast
Molecular cloning of a functio ...... chanism of receptor activation
@en
Molecular cloning of a functio ...... chanism of receptor activation
@en-gb
Molecular cloning of a functio ...... chanism of receptor activation
@nl
prefLabel
Molecular cloning of a functio ...... chanism of receptor activation
@ast
Molecular cloning of a functio ...... chanism of receptor activation
@en
Molecular cloning of a functio ...... chanism of receptor activation
@en-gb
Molecular cloning of a functio ...... chanism of receptor activation
@nl
P2093
P921
P3181
P1433
P1476
Molecular cloning of a functio ...... chanism of receptor activation
@en
P2093
P304
P3181
P356
10.1016/0092-8674(91)90261-V
P407
P577
1991-03-22T00:00:00Z