The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo
about
Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modificationPDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinityThe Role of RPGR and Its Interacting Proteins in CiliopathiesMembrane protein transport in photoreceptors: the function of PDEδ: the Proctor lectureMistrafficking of prenylated proteins causes retinitis pigmentosa 2.De Novo Occurrence of a Variant in ARL3 and Apparent Autosomal Dominant Transmission of Retinitis PigmentosaRPGR: Its role in photoreceptor physiology, human disease, and future therapies.The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.Single-residue posttranslational modification sites at the N-terminus, C-terminus or in-between: To be or not to be exposed for enzyme accessRPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner.ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.Rab, Arf, and Arl-Regulated Membrane Traffic in Cortical Neuron Migration.Localizing the RPGR protein along the cilium: a new method to determine efficacies to treat RPGR mutations.Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3.PDE6D binds to the C-terminus of RPGR in a prenylation-dependent manner.The N- and C-terminal ends of RPGR can bind to PDE6δ.Prenylated retinal ciliopathy protein RPGR interacts with PDE6δ and regulates ciliary localization of Joubert syndrome-associated protein INPP5E.Evolutionary Characterization of the Retinitis Pigmentosa GTPase Regulator Gene.Staccato/Unc-13-4 controls secretory lysosome-mediated lumen fusion during epithelial tube anastomosis.Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6.Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria.Endosome maturation factors Rabenosyn-5/VPS45 and caveolin-1 regulate ciliary membrane and polycystin-2 homeostasis.Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease
P2860
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P2860
The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo
description
2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2013 թվականի մայիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@ast
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en-gb
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@nl
type
label
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@ast
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en-gb
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@nl
prefLabel
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@ast
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en-gb
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The interplay between RPGR, PD ...... argeting of farnesylated cargo
@en
P2093
Ingrid Vetter
Katja Gotthardt
Mandy Miertzschke
Yong-Xiang Chen
P2860
P304
P3181
P356
10.1038/EMBOR.2013.37
P407
P577
2013-05-01T00:00:00Z