hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity
about
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseRibonucleotides in DNA: Origins, repair and consequencesHuman Primpol1: a novel guardian of stalled replication forksMitochondrial DNA replication: a PrimPol perspective.Processing ribonucleotides incorporated during eukaryotic DNA replication.Molecular basis for PrimPol recruitment to replication forks by RPAMitochondrial genome maintenance in health and disease.DNA polymerases in the mitochondria: A critical review of the evidence.Molecular dissection of the domain architecture and catalytic activities of human PrimPol.Human PrimPol mutation associated with high myopia has a DNA replication defect.Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes.Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.SLFN11 inhibits checkpoint maintenance and homologous recombination repair.Replication protein A and more: single-stranded DNA-binding proteins in eukaryotic cells.Human PrimPol activity is enhanced by RPA.Insights into the Molecular Mechanism of Polymerization and Nucleoside Reverse Transcriptase Inhibitor Incorporation by Human PrimPol.PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells.PrimPol prevents APOBEC/AID family mediated DNA mutagenesisOxidative DNA damage stalls the human mitochondrial replisomeStructure and mechanism of human PrimPol, a DNA polymerase with primase activity.TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPolThe PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR).Mechanisms of Post-Replication DNA RepairMolecular mechanisms of DNA replication checkpoint activationKinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7,8-dihydro-8-oxo-2'-deoxyguanosine.The essential kinase ATR: ensuring faithful duplication of a challenging genome.DNA replication stress: from molecular mechanisms to human disease.Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides.PrimPol-Prime Time to Reprime.PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage.PrimPol-A new polymerase on the block.Eukaryotic DNA Polymerases in Homologous Recombination.Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches.Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same ObstaclePolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities.Optimization of the expression, purification and polymerase activity reaction conditions of recombinant human PrimPol.DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol.Starting over: Primpol reprimes after chain termination.
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hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity
description
2013 nî lūn-bûn
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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
@wuu
name
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@ast
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en-gb
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@nl
type
label
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@ast
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en-gb
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@nl
prefLabel
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@ast
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en-gb
hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@nl
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hPrimpol1/CCDC111 is a human D ...... aintenance of genome integrity
@en
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Jiamin Cui
Jiangman Lou
Yingying Sun
P2860
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P356
10.1038/EMBOR.2013.159
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2013-12-01T00:00:00Z