c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
about
Regulation of the intrinsic apoptosis pathway by reactive oxygen speciesReduced expression of the retinoblastoma protein shows that the related signaling pathway is essential for mediating the antineoplastic activity of erufosineThe S-nitrosylation status of PCNA localized in cytosol impacts the apoptotic pathway in a Parkinson's disease paradigmCaspase-9: structure, mechanisms and clinical applicationRegulation of the Apaf-1-caspase-9 apoptosomeA multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue lightNormal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases.Caspases and kinases in a death grip.Cellular mechanisms controlling caspase activation and function.Evading apoptosis in cancer.Caspase-9 as a therapeutic target for treating cancer.Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro.Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias.Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8.Imatinib prevents beta cell death in vitro but does not improve islet transplantation outcome.Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9.The impact of phosphatases on proliferative and survival signaling in cancer.Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.
P2860
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P2860
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@nl
type
label
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@nl
prefLabel
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@nl
P2093
P921
P356
P1476
c-Abl tyrosine kinase regulate ...... optotic response to DNA damage
@en
P2093
Ajit Bharti
Deepak Raina
Pramod Pandey
Ralph Weichselbaum
Rehan Ahmad
Surender Kharbanda
P304
P356
10.1074/JBC.M413787200
P407
P577
2005-03-25T00:00:00Z