Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor
about
Complex Commingling: Nucleoporins and the Spindle Assembly CheckpointA Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration.Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry.A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly CheckpointNuclear pore proteins and the control of genome functionsPhosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment.The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells"Wait anaphase" signals are not confined to the mitotic spindle.Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics.Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing proteinNup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region.DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity.The Nuclear Matrix Protein Megator Regulates Stem Cell Asymmetric Division through the Mitotic Checkpoint Complex in Drosophila Testes.Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachmentDNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint.Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter.Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.A dual molecular analogue tuner for dissecting protein function in mammalian cellsMAD2γ, a novel MAD2 isoform, reduces mitotic arrest and is associated with resistance in testicular germ cell tumors.BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancerA novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1.Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase.Signalling dynamics in the spindle checkpoint response.How oocytes try to get it right: spindle checkpoint control in meiosis.The spindle assembly checkpoint promotes chromosome bi-orientation: A novel Mad1 role in chromosome alignment.Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission YeastAneuploidy in Cancer and Aging.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.Nuclear pores set the speed limit for mitosis.Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions.Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore.Chromosomal instability, aneuploidy, and cancer.Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies.Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation.Mad1 at the Golgi apparatus: a story beyond kinetochores.Distinct responses to reduplicated chromosomes require distinct Mad2 responses.Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A.Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing.
P2860
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P2860
Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@ast
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en-gb
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@nl
type
label
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@ast
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en-gb
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@nl
prefLabel
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@ast
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en-gb
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@nl
P2093
P2860
P50
P3181
P1433
P1476
Nuclear pores protect genome i ...... 1-dependent anaphase inhibitor
@en
P2093
Håkon Kirkeby Buch
Jagesh V Shah
Jennifer Corona
Philippe Collin
Prasad V Jallepalli
P2860
P304
P3181
P356
10.1016/J.CELL.2014.01.010
P407
P577
2014-02-27T00:00:00Z