Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes
about
Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1SGF29 and Sry pathway in hepatocarcinogenesisCell cycle-related genes p57kip2, Cdk5 and Spin in the pathogenesis of neural tube defects.A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.Histones: at the crossroads of peptide and protein chemistry.The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling.Developing Spindlin1 small-molecule inhibitors by using protein microarrays.Deficiency of the multi-copy mouse Y gene Sly causes sperm DNA damage and abnormal chromatin packagingInsights into newly discovered marks and readers of epigenetic information.SSTY proteins co-localize with the post-meiotic sex chromatin and interact with regulators of its expression.Tudor: a versatile family of histone methylation 'readers'.Mind the methyl: methyllysine binding proteins in epigenetic regulation.Acidic domains differentially read histone H3 lysine 4 methylation status and are widely present in chromatin-associated proteins.Spindlin 1 is essential for metaphase II stage maintenance and chromosomal stability in porcine oocytes.The histone code reader SPIN1 controls RET signaling in liposarcoma.Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions.A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.The histone code reader Spin1 controls skeletal muscle development.SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer.Developing diazirine-based chemical probes to identify histone modification 'readers' and 'erasers'.SPIN1, negatively regulated by miR-148/152, enhances Adriamycin resistance via upregulating drug metabolizing enzymes and transporter in breast cancer.SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma
P2860
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P2860
Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@ast
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en-gb
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@nl
type
label
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@ast
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en-gb
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@nl
prefLabel
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@ast
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en-gb
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@nl
P2093
P2860
P356
P1433
P1476
Nucleolar protein Spindlin1 re ...... s the expression of rRNA genes
@en
P2093
Huihui Zhang
Ruiming Xu
Weixiang Wang
Xiaodong Zhang
Xiaojun Ding
P2860
P304
P356
10.1038/EMBOR.2011.184
P407
P577
2011-11-01T00:00:00Z