Quenched hydrogen/deuterium exchange NMR characterization of amyloid-beta peptide aggregates formed in the presence of Cu2+ or Zn2+
about
Aβ peptide fibrillar architectures controlled by conformational constraints of the monomerBeta-barrel models of soluble amyloid beta oligomers and annular protofibrils.Molecular-level examination of Cu2+ binding structure for amyloid fibrils of 40-residue Alzheimer's β by solid-state NMR spectroscopy.Zn(++) binding disrupts the Asp(23)-Lys(28) salt bridge without altering the hairpin-shaped cross-β Structure of Aβ(42) amyloid aggregates.Nanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide.Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1-40) and zinc(II)-bound amyloid-β(1-42) with dynamics.Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity.Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death.Copper prevents amyloid-β(1-42) from forming amyloid fibrils under near-physiological conditions in vitro.The role of histidines in amyloid β fibril assembly.Role of zinc in human islet amyloid polypeptide aggregation.Ca(2+) enhances Aβ polymerization rate and fibrillar stability in a dynamic manner.Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β PeptidesRapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β PeptidesSide-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions
P2860
Q28744420-28AB216E-4E1C-49BC-A450-B1CC54EA3185Q30156038-2BCCF2FF-00CE-48DE-B1DB-C06708B59F5EQ34779975-C24C9E00-C96E-439B-A498-A5F097DBA9A8Q35815889-B29CC4FF-0A1B-4CA2-83D7-5F4F824C1CE0Q36652253-66039BC9-C756-43B9-820D-600D9C17957CQ36950757-F54493FE-03A8-449C-9679-AE8E14F36486Q37848098-0A2939EF-1777-4544-9F39-A2969A14DC58Q38016898-DA67CA33-764D-4468-9C4B-773EB9E27498Q38991747-4E5F5759-6AA4-4FBC-9CCA-D2C65797BF8EQ41957589-51FB350E-A7AC-4677-B5A2-508FD6F517C5Q42090533-D4BF1C67-2262-4635-98EE-5E82C13268EDQ42732430-1151288C-C88C-4DD3-BFA2-03070708D587Q43876883-5E78298A-517A-4C04-89CA-BF37DDA02866Q58045283-0C42DEA5-4C9B-4536-89ED-9533DD082DA5Q58045285-08499CC6-5FF6-4979-B688-5C79CE25B3C1Q58799799-E988DDD0-A1E4-4991-9484-1CA79F01F5D1
P2860
Quenched hydrogen/deuterium exchange NMR characterization of amyloid-beta peptide aggregates formed in the presence of Cu2+ or Zn2+
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@ast
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en-gb
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@nl
type
label
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@ast
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en-gb
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@nl
prefLabel
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@ast
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en-gb
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@nl
P2093
P1433
P1476
Quenched hydrogen/deuterium ex ...... n the presence of Cu2+ or Zn2+
@en
P2093
Anders Ohman
Anders Olofsson
Malin Lindhagen-Persson
Monika Vestling
P304
P356
10.1111/J.1742-4658.2009.07113.X
P407
P577
2009-06-22T00:00:00Z