N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity
about
Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo.Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiencyInhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasisDe novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and femalesNuclear translocation of hARD1 contributes to proper cell cycle progressionExpression of human NAA11 (ARD1B) gene is tissue-specific and is regulated by DNA methylationBiochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defectsA splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndromeThe biological functions of Naa10 - From amino-terminal acetylation to human diseaseAcetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis.αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor ReceptorCdc42 promotes transendothelial migration of cancer cells through β1 integrin.Rac1 recruitment to the archipelago structure of the focal adhesion through the fluid membrane as revealed by single-molecule analysisProtein N-terminal acetyltransferases in cancer.N-α-acetyltransferase 10 protein is a negative regulator of 28S proteasome through interaction with PA28β.β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration.GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis.microRNA-342-5p and miR-608 inhibit colon cancer tumorigenesis by targeting NAA10.Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein.Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy.The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitriesDepletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathwayDevelopmental roles of protein N-terminal acetylation.Transduction motif analysis of gastric cancer based on a human signaling network.High expression of Naa10p associates with lymph node metastasis and predicts favorable prognosis of oral squamous cell carcinoma.Downregulation of miR-25 modulates non-small cell lung cancer cells by targeting CDC42.Arhgef7 promotes activation of the Hippo pathway core kinase LatsmiR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6.A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse.The N-terminal acetyltransferase Naa10 is essential for zebrafish development.NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma.Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis.Identification of Nucleobindin-2 as a Potential Biomarker for Breast Cancer Metastasis Using iTRAQ-based Quantitative Proteomic Analysis.NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expressionIdentification of PA28β as a potential novel biomarker in human esophageal squamous cell carcinoma.NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.Inverse correlation between Naa10p and MMP-9 expression and the combined prognostic value in breast cancer patients.ARD1 contributes to IKKβ-mediated breast cancer tumorigenesis
P2860
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P248
Q27939409-31589732-4290-442F-83FF-0665284B6030Q28241532-F65D4942-FB71-4205-8332-1BB73EEF2BB7Q28241878-E8AB28E4-DBC0-4CC0-B19F-00220F5A01A7Q28245379-6CAABA75-249F-47DB-9CB3-4B8CE7B5CBB5Q28246222-109D77C7-3FEB-4958-AFD0-870CE7E5DD27Q28252069-E870CFE9-5C15-4D01-B064-E353172D5D7BQ28253618-A3F12399-2B80-4A83-83A4-C49A58251C70Q28305932-3B308AD8-7B46-4D11-A3B2-5DD592274B06Q28638824-D686F328-F26C-4E3C-AFE5-956B5C9C1B23Q30353562-1AF43D48-8980-483B-9184-EFAB7ADF1770Q30375559-84E65F1B-732C-4AAF-9F11-4B027AF5CBA5Q30528220-04EC3CB2-F0BE-4545-950F-D8C97BD85C16Q30538902-0915E835-9F5F-457A-95EE-DD1D01478CF8Q34258775-25A2D268-9829-47E9-A693-3DA215F705B2Q34691587-151175C9-5D3A-4AFB-89FB-B9F273350B4CQ35571905-85A16B63-8568-4723-AEAE-9FE3EC6509E0Q36546633-FAA067B4-B7E7-4447-92D6-326E3670A785Q36771922-5A1621F8-8E4C-4433-BF1E-09DB51C56499Q37350958-AA54DA6A-BD2D-4672-884E-1D1DFBF8C3D9Q37629548-EFAA5F09-E189-47A9-836F-85347BBA219CQ37710032-4C50A8AC-2E87-4F76-B67E-F7379F77065EQ38292041-FCF8DC73-46DD-45BA-8876-11DE3D7D0B7BQ38446887-8F06B521-A71C-434C-8CF7-D09F9E388444Q38476822-3A1B31EB-EF4F-41C1-9436-9B25A8511C5DQ38812097-746EDB91-EBD7-4E91-AF22-1A2077D4E684Q38937139-179F4468-4F99-46E8-AC89-1BD034F3F9BCQ38937708-6885285A-2C21-4EA3-BF08-704F2DB1D751Q39239384-E94C6DAA-938A-4C13-9166-3ECF701F9164Q39435733-EF59DF4F-FE2B-4BFE-9896-41A28A05B957Q40649402-56C59CD6-7D82-4D64-A610-370928D9D0DFQ41093191-566A565B-DBD7-4DD2-95A6-082DFBCE089BQ41606283-EC245AD4-CB14-4FA1-A571-8D668222E351Q41721639-C7388082-7EEC-4D3E-9F10-BD931BB63910Q42377234-0BC1027B-E32C-4B9C-8704-4BAB06640DD4Q47666341-10936560-5B1F-4CAB-9D4B-5A946A02859AQ52646493-0AAE8E8B-25C4-4B0C-94A0-E863606DA076Q53255926-C45673F6-82C2-4D8F-89A4-31A0F7849B92Q58699419-90AFB329-CC1E-48A7-B8F3-A095CC6C3B18
P2860
N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@ast
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en-gb
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@nl
type
label
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@ast
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en-gb
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@nl
prefLabel
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@ast
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en-gb
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@nl
P2093
P50
P1433
P1476
N-α-acetyltransferase 10 prote ...... inhibiting Cdc42/Rac1 activity
@en
P2093
Chee-Yin Chai
Chi-Kuan Chen
Chia-Chun Chi
Chih-Jen Yang
George Rosenberger
Gunnar Johansson
Hou-Jung Shih
Hsin-Jung Kao
Hsin-Yi Lu
Jang-Ming Lee
P304
P356
10.1016/J.CCR.2010.11.010
P407
P577
2011-02-03T00:00:00Z