Structure of the human aggrecan gene: exon-intron organization and association with the protein domains
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Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy studySpecies-specific alternative splicing of the epidermal growth factor-like domain 1 of cartilage aggrecanAge-related changes in the content of the C-terminal region of aggrecan in human articular cartilageStructure of the human beta2-glycoprotein I (apolipoprotein H) gene.A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans.The protein fold of the hyaluronate-binding proteoglycan tandem repeat domain of link protein, aggrecan and CD44 is similar to that of the C-type lectin superfamily.Identification of a locus for a form of spondyloepiphyseal dysplasia on chromosome 15q26.1: exclusion of aggrecan as a candidate geneSequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosisThe role of aggrecan in normal and osteoarthritic cartilage.Alternative splicing of the unique "PLUS" domain of chicken PG-M/versican is developmentally regulated.Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan.An overview of the etiology of otosclerosis.Aggrecan: A Target Molecule of Autoimmune Reactions.L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis.Quantification of aggrecan and link-protein mRNA in human articular cartilage of different ages by competitive reverse transcriptase-PCR.Domain shuffling and the evolution of vertebrates.Sulphation heterogeneity in the trisaccharide (GalNAcSbeta1, 4GlcAbeta1,3GalNAcS) isolated from the non-reducing terminal of human aggrecan chondroitin sulphate.A remote upstream element regulates tissue-specific expression of the rat aggrecan gene.Regulatory activities of the 5'- and 3'-untranslated regions and promoter of the human aggrecan gene.Clinical Characterization of Patients With Autosomal Dominant Short Stature due to Aggrecan Mutations.Knee joint immobilization decreases aggrecan gene expression in the meniscus.A human-specific polymorphism in the coding region of the aggrecan gene. Variable number of tandem repeats produce a range of core protein sizes in the general population.Structural and functional analysis of the chick chondroitin sulfate proteoglycan (aggrecan) promoter and enhancer region.Characterization of the bovine aggrecan gene: genomic structure and physical and linkage mapping.The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness.Utilization of a Recombinant Substrate rAgg1 to Study the Biochemical Properties of Aggrecanase in Cell Culture Systems
P2860
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P2860
Structure of the human aggrecan gene: exon-intron organization and association with the protein domains
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Structure of the human aggreca ...... ation with the protein domains
@ast
Structure of the human aggreca ...... ation with the protein domains
@en
Structure of the human aggreca ...... ation with the protein domains
@en-gb
Structure of the human aggreca ...... ation with the protein domains
@nl
type
label
Structure of the human aggreca ...... ation with the protein domains
@ast
Structure of the human aggreca ...... ation with the protein domains
@en
Structure of the human aggreca ...... ation with the protein domains
@en-gb
Structure of the human aggreca ...... ation with the protein domains
@nl
prefLabel
Structure of the human aggreca ...... ation with the protein domains
@ast
Structure of the human aggreca ...... ation with the protein domains
@en
Structure of the human aggreca ...... ation with the protein domains
@en-gb
Structure of the human aggreca ...... ation with the protein domains
@nl
P2093
P2860
P356
P1433
P1476
Structure of the human aggreca ...... ation with the protein domains
@en
P2093
A Ratcliffe
G D Palmer
P A Rivers
W B Valhmu
P2860
P304
P356
10.1042/BJ3090535
P407
P478
309 ( Pt 2)
P577
1995-07-15T00:00:00Z