Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid
about
Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamilyIdentification, characterization and structure of a new Delta class glutathione transferase isoenzymeLow-dose pharmacokinetics and oral bioavailability of dichloroacetate in naive and GST-zeta-depleted rats.Identification, characterization, and crystal structure of the Omega class glutathione transferasesPrenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetateBinding and kinetic mechanisms of the Zeta class glutathione transferaseToxicokinetics of bromodichloroacetate in B6C3F1 mice.Physiologically based pharmacokinetic modeling of dibromoacetic acid in F344 rats.Metabolism of trichloroethylenePolymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in Spain.Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism.Dichloroacetate- and Trichloroacetate-Induced Modulation of Superoxide Dismutase, Catalase, and Glutathione Peroxidase Activities and Glutathione Level in the livers of Mice after Subacute and Subchronic exposure.Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1.Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Do Antioxidant Enzymes and Glutathione Play Roles in the Induction of Hepatic Oxidative Stress in Mice upon Subchronic Exposure to Mixtures of Dichloroacetate and Trichloroacetate?Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferasesDCA promotes progression of neuroblastoma tumors in nude mice.Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and miceGlutathione s-transferases in pediatric cancer.The use of glutathione transferase-knockout mice as pharmacological and toxicological models.Marine glutathione S-transferases.Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.Trichloroethylene risk assessment: a review and commentary.Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice.Multiple roles for plant glutathione transferases in xenobiotic detoxification.Pharmacogenetic considerations with dichloroacetate dosing.Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.Multiple glutathione S-transferase genes: identification and expression in oriental fruit fly, Bactrocera dorsalis.In vitro toxicity and genotoxicity assessment of disinfection by-products, organic N-chloramines.Functional classification and biochemical characterization of a novel rho class glutathione S-transferase in Synechocystis PCC 6803Kinetics of trihalogenated acetic acid metabolism and isoform specificity in liver microsomes.Evolution of the catalytic activity of Arabidopsis thaliana glutathione transferase zeta class-1 by saturation mutagenesis.Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique.Characterization of the fluoroacetate detoxication enzymes of rat liver cytosol.Developmental roles of tyrosine metabolism enzymes in the blood-sucking insect Rhodnius prolixus.Characterization of catalytic activity and structure of selenocysteine-containing hGSTZ1c-1c based on site-directed mutagenesis and computational analysis.
P2860
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P2860
Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@ast
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en-gb
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@nl
type
label
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@ast
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en-gb
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@nl
prefLabel
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@ast
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en-gb
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@nl
P2093
P2860
P356
P1433
P1476
Glutathione transferase zeta c ...... oacetic acid to glyoxylic acid
@en
P2093
P2860
P356
10.1042/BJ3310371
P407
P478
331 ( Pt 2)
P577
1998-04-15T00:00:00Z