Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene
about
Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alphaCloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alphaDecreased sucrase and lactase activity in iron deficiency is accompanied by reduced gene expression and upregulation of the transcriptional repressor PDX-1Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivoGata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during developmentKruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epitheliumChanging genes; losing lactaseMapping of HNF4alpha target genes in intestinal epithelial cellsDifferential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.Differential expression of Homeobox C11 protein in water buffalo Bubalus bubalis and its putative 3D structure.Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins.Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter.Analysis of the regulation of the A33 antigen gene reveals intestine-specific mechanisms of gene expression.Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development.Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.Transcriptional networks driving enhancer function in the CFTR gene.Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.Proteomic screen defines the hepatocyte nuclear factor 1alpha-binding partners and identifies HMGB1 as a new cofactor of HNF1alpha.Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta.Differential regulation of the glucose-6-phosphatase TATA box by intestine-specific homeodomain proteins CDX1 and CDX2Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system.Characterization of the human peptide transporter PEPT1 promoter: Sp1 functions as a basal transcriptional regulator of human PEPT1.Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines.Hepatocyte nuclear factor 4alpha enhances the hepatocyte nuclear factor 1alpha-mediated activation of transcriptionPrecise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression.Genome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2)T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro.Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4.Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.
P2860
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P2860
Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@ast
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en-gb
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@nl
type
label
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@ast
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en-gb
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@nl
prefLabel
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@ast
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en-gb
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@nl
P2093
P2860
P356
P1433
P1476
Interaction between the homeod ...... ctase-phlorizin hydrolase gene
@en
P2093
C Mitchelmore
H Sjöström
J T Troelsen
N Spodsberg
P2860
P304
P356
10.1042/BJ3460529
P407
P478
P577
2000-03-01T00:00:00Z