Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation
about
Human eukaryotic release factor 3a depletion causes cell cycle arrest at G1 phase through inhibition of the mTOR pathwayTranslational readthrough potential of natural termination codons in eucaryotes--The impact of RNA sequenceG1 to S phase transition protein 1 induces apoptosis signal-regulating kinase 1 activation by dissociating 14-3-3 from ASK1Polyglycine expansions in eRF3/GSPT1 are associated with gastric cancer susceptibilityEvolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components.Xp11.22 deletions encompassing CENPVL1, CENPVL2, MAGED1 and GSPT2 as a cause of syndromic X-linked intellectual disability.L-Ilf3 and L-NF90 traffic to the nucleolus granular component: alternatively-spliced exon 3 encodes a nucleolar localization motifThe interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay.The evolutionary and functional diversity of classical and lesser-known cytoplasmic and organellar translational GTPases across the tree of lifePathologic effects of RNase-L dysregulation in immunity and proliferative control.Translation termination efficiency modulates ATF4 response by regulating ATF4 mRNA translation at 5' short ORFsHuman nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complexStudies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility.Role of oxygen consumption in hypoxia protection by translation factor depletion.Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels.Decoding Mammalian Ribosome-mRNA States by Translational GTPase ComplexesFine-mapping and family-based association analyses of prostate cancer risk variants at Xp11.Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.Proteasomal degradation of human release factor eRF3a regulates translation termination complex formation.In Aspergillus nidulans the suppressors suaA and suaC code for release factors eRF1 and eRF3 and suaD codes for a glutamine tRNA.PABP enhances release factor recruitment and stop codon recognition during translation termination.eRF3b, a biomarker for hepatocellular carcinoma, influences cell cycle and phosphoralation status of 4E-BP1.GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding.Prion-dependent lethality of sup45 mutants in Saccharomyces cerevisiae.Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.GGCn polymorphism of eRF3a/GSPT1 gene and breast cancer susceptibility.Translation termination-dependent deadenylation of MYC mRNA in human cells.
P2860
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P2860
Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Involvement of human release f ...... termination complex formation
@ast
Involvement of human release f ...... termination complex formation
@en
Involvement of human release f ...... termination complex formation
@en-gb
Involvement of human release f ...... termination complex formation
@nl
type
label
Involvement of human release f ...... termination complex formation
@ast
Involvement of human release f ...... termination complex formation
@en
Involvement of human release f ...... termination complex formation
@en-gb
Involvement of human release f ...... termination complex formation
@nl
prefLabel
Involvement of human release f ...... termination complex formation
@ast
Involvement of human release f ...... termination complex formation
@en
Involvement of human release f ...... termination complex formation
@en-gb
Involvement of human release f ...... termination complex formation
@nl
P2093
P2860
P3181
P1476
Involvement of human release f ...... termination complex formation
@en
P2093
Catherine Le Goff
Céline Chauvin
Dialo Diop
Olivier Jean-Jean
Samia Salhi
P2860
P304
P3181
P356
10.1128/MCB.25.14.5801-5811.2005
P407
P577
2005-07-01T00:00:00Z