Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
about
A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expressionThe WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functionsReciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditionsVitamin D receptor agonists: suitable candidates as novel therapeutic options in autoimmune inflammatory myopathyWdr68 requires nuclear access for craniofacial developmentStructures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate RecognitionExamination of the expanding pathways for the regulation of p21 expression and activity.Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitorsdDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species.The kinase Mirk is a potential therapeutic target in osteosarcoma.The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen speciesDepleting Mirk Kinase Increases Cisplatin Toxicity in Ovarian Cancer Cells.Cell death-resistance of differentiated myotubes is associated with enhanced anti-apoptotic mechanisms compared to myoblasts.The role of mirk kinase in sarcomasKAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiationNew targets to treat obesity and the metabolic syndrome.IRES-mediated translation of the pro-apoptotic Bcl2 family member PUMA.The Kinase Mirk/dyrk1B: A Possible Therapeutic Target in Pancreatic CancerThe C-terminal region of E1A: a molecular tool for cellular cartography.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy.Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/RB2.Down-regulation of CIBZ, a novel substrate of caspase-3, induces apoptosis.Mirk/dyrk1B Kinase in Ovarian Cancer.The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling.Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.Signaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation.Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.Dietary resveratrol confers apoptotic resistance to oxidative stress in myoblasts.Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.
P2860
Q21284144-6C2EF5B7-64FC-4A6D-A2C2-6AB5B009BF05Q24302518-36AD5EED-A170-4EA5-8D9A-C2CC83B36392Q24319987-864168D6-346E-4834-B457-25C6E4648ECBQ26849424-DF4692F1-4AEE-468A-A522-44A88E1C5494Q27319944-69B8E08F-55A4-444F-8B68-62A061ACAF8BQ27678087-CD58126C-1CFF-446F-AABA-718BC06ACE19Q27692024-C03F8008-94D1-4828-9708-3328159B1BBDQ28541616-DB243B0F-06D9-4BC8-9FA5-080FC8CC5383Q33242077-56D8BE4E-D17F-4B81-878D-95892E71F94EQ33427731-842BE022-45B4-4001-AAAF-DF28C4A16053Q33521423-11EE37E4-8C31-4C22-A35E-7D11B60C1CCCQ33776829-E867DF9A-ECD2-4951-902A-1394068DEFFDQ34339955-13F31A2A-D68E-424A-922F-DBE7E1DC5176Q34609532-B6FE1D8E-3F22-488D-A5CB-C27A76A48D7FQ34928886-26D352DA-845D-4BDF-826F-3946C1EFE11AQ36022225-FD144187-38C6-4F71-A802-61CB978AFF3DQ36068914-ECDE7FDF-66FF-4628-B51D-E8A3CFCC9A86Q36477557-F8C2D7FF-116B-4186-A7C0-F2E944DB5C59Q37334250-84612467-CAB6-4AEC-80D4-53F5D51C18AFQ37980172-7C1BD3C8-CB25-41DE-8039-6BD068EA8FA5Q38214413-D0381C56-3504-495B-ABAC-A51A84250485Q38290011-913F6534-5473-4FDF-A5D7-DFE86C6E0BD4Q39653282-BB85FBE0-0E69-473E-827F-09B870C828DDQ39997162-AB7C1538-3F14-4EC7-A10B-CA5BC0741656Q40044634-F4595562-2A30-4922-92C8-B05CDB88C0AEQ40356655-EC943776-4790-4321-89C7-27809075EDD2Q41782221-D3D8F8A9-BFD2-4190-98B7-62B45C3C3CA0Q42242386-4EB21B5C-6EAB-42A1-B483-0EBDDB3D8D5EQ42360652-6AB79885-CAF6-4684-B823-D889679BBC09Q42708880-CC764A56-3A8D-4EF6-9117-B287E8AD2598Q42811646-E2AF2833-7115-4764-985F-F07758E67DABQ45070601-2B3675BD-B378-4E89-ACC5-446E5769D929Q47654334-8C2058D4-0778-410B-9BE0-6E7AA782E146Q52641599-6ED2F923-6B72-4378-9042-593F36A57781Q54117942-6B1C9B2B-4DC6-44AD-8188-B45653800BA2
P2860
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@ast
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en-gb
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@nl
type
label
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@ast
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en-gb
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@nl
prefLabel
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@ast
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en-gb
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@nl
P2093
P2860
P356
P1476
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
@en
P2093
Daina Z Ewton
Eileen Friedman
Seunghwan Lim
Stephen E Mercer
Thomas R Mazur
Xiaobing Deng
P2860
P304
25788-25801
P356
10.1074/JBC.M413594200
P407
P577
2005-04-25T00:00:00Z