Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
about
Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein coreASAP, a novel protein complex involved in RNA processing and apoptosisStructural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.Identification of the gene transcription repressor domain of Gli3Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayStructural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/CiThe negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteinsGli proteins and the control of spinal-cord patterningMIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcriptionSuppressor of fused regulates Gli activity through a dual binding mechanismThe output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteinsThe Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolutionTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsDecoding the phosphorylation code in Hedgehog signal transductionContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyCharacterization of the physical interaction of Gli proteins with SUFU proteinsA novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse modelMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedSAP18 promotes Krüppel-dependent transcriptional repression by enhancer-specific histone deacetylation.Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary ciliumIdentification and analysis of plasticity-induced late-response genes.Chick Hairy1 protein interacts with Sap18, a component of the Sin3/HDAC transcriptional repressor complex.GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathwaysMechanism and evolution of cytosolic Hedgehog signal transductionSmoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail.Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis.Regulation of Hedgehog signaling: a complex story.Su(fu) switches Rdx functions to fine-tune hedgehog signaling in the Drosophila wing disk.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium.The transcriptional repressor domain of Gli3 is intrinsically disorderedModulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.Clinical implications of hedgehog signaling pathway inhibitorsDual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural developmentHyperplastic discs differentially regulates the transcriptional outputs of hedgehog signaling
P2860
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P2860
Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@ast
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en-gb
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@nl
type
label
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@ast
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en-gb
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@nl
prefLabel
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@ast
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en-gb
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@nl
P2860
P3181
P356
P1476
Suppressor of Fused represses ...... AP18-mSin3 corepressor complex
@en
P2093
J Michael Bishop
Steven Yan Cheng
P2860
P304
P3181
P356
10.1073/PNAS.082096999
P407
P577
2002-04-01T00:00:00Z