Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts
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Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfateGlycoarray Technologies: Deciphering Interactions from Proteins to Live Cell ResponsesN-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor bindingChemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry.Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions.Generating heparan sulfate saccharide libraries for glycomics applications.Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions.Heparan sulfate is required for embryonic stem cells to exit from self-renewalExtended N-sulfated domains reside at the nonreducing end of heparan sulfate chains.Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?Effect of heparin oligomer chain length on the activation of valvular interstitial cells.The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor.Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma.FGF2 binding, signaling, and angiogenesis are modulated by heparanase in metastatic melanoma cellsA survey of the year 2002 commercial optical biosensor literature.Dermatan sulfate is involved in the tumorigenic properties of esophagus squamous cell carcinoma.Cytokines and growth factors cross-link heparan sulfate.Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling.Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificityAchieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors.Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signalingEnabling methodology for the end functionalization of glycosaminoglycan oligosaccharides.Biological implications of glycosaminoglycan interactions with haemopoietic cytokines.The role of the biochemical and biophysical environment in chondrogenic stem cell differentiation assays and cartilage tissue engineering.Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer.Heparan sulfate in angiogenesis: a target for therapy.Octasaccharide is the minimal length unit required for efficient binding of cyclophilin B to heparin and cell surface heparan sulphate.Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.Fabrication of carbohydrate surfaces by using nonderivatised oligosaccharides, and their application to measuring the assembly of sugar-protein complexes.Fractone-heparan sulphates mediate FGF-2 stimulation of cell proliferation in the adult subventricular zone.Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain.The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins.Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.Structural determinants of heparan sulphate modulation of GDNF signalling.The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex.
P2860
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P2860
Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@ast
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@en
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@nl
type
label
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@ast
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@en
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@nl
prefLabel
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@ast
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@en
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@nl
P2093
P2860
P921
P356
P1433
P1476
Fibroblast growth factor-2 bin ...... ion of rat mammary fibroblasts
@en
P2093
John T Gallagher
Malcolm Lyon
Philip S Rudland
P2860
P304
P356
10.1042/BJ20011718
P407
P577
2002-08-15T00:00:00Z