Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
about
beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in miceIn silico Approach for Anti-Thrombosis Drug Discovery: P2Y1R Structure-Based TCMs ScreeningA "hot" topic in dyslipidemia management--"how to beat a flush": optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBTInflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages.Does nicotinic acid (niacin) lower blood pressure?Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.GRK2 and β-arrestins in cardiovascular disease: Something old, something new.Prevalence and Specificity of the Abnormal Niacin Response: A Potential Endophenotype Marker in Schizophrenia.1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.High-density lipoprotein cholesterol: current perspective for clinicians.The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.Nicotinic acid inhibits glioma invasion by facilitating Snail1 degradationPharmacogenomics of high-density lipoprotein-cholesterol-raising therapies.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.Investigation of niacin on parameters of metabolism in a physiologic dose: randomized, double-blind clinical trial with three different dosages.Elucidation of signaling and functional activities of an orphan GPCR, GPR81.Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule.
P2860
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P2860
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
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2005 nî lūn-bûn
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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
@zh-mo
2005年論文
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2005年论文
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name
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@ast
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en-gb
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@nl
type
label
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@ast
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en-gb
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@nl
prefLabel
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@ast
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en-gb
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@nl
P2860
P356
P1476
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
@en
P2093
Nicholas B Pike
P2860
P304
P356
10.1172/JCI27160
P407
P577
2005-12-01T00:00:00Z