The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B - Wikidata - awgldk - TriplyDB

The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B

The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B

http://www.wikidata.org/entity/Q24537160

about

The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I Multifaceted Roles of ALG-2 in Ca(2+)-Regulated Membrane Trafficking Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization.Involvement of the penta-EF-hand protein Pef1p in the Ca2+-dependent regulation of COPII subunit assembly in Saccharomyces cerevisiae.The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein Structural and Functional Study of Apoptosis-linked Gene-2·Heme-binding Protein 2 Interactions in HIV-1 Production Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2 Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.The ESCRT system is required for hepatitis C virus production.Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repair.Proline-rich regions and motifs in trafficking: from ESCRT interaction to viral exploitation.The structural biology of HIV-1: mechanistic and therapeutic insights Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1.ESCRT & Co.Structure and function of ALG-2, a penta-EF-hand calcium-dependent adaptor protein.Differential requirements of mammalian ESCRTs in multivesicular body formation, virus budding and cell division.Evolutionary and physical linkage between calpains and penta-EF-hand Ca2+-binding proteins.Calcium signaling in membrane repair.Deregulated ALG-2/HEBP2 axis alters microtubule dynamics and mitotic spindle behavior to stimulate cancer development.Influence of calcium/calmodulin on budding of Ebola VLPs: implications for the involvement of the Ras/Raf/MEK/ERK pathway.ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction.The apoptosis linked gene ALG-2 is dysregulated in tumors of various origin and contributes to cancer cell viability.Prediction of a new ligand-binding site for type 2 motif based on the crystal structure of ALG-2 by dry and wet approaches.POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila.The calcium-binding protein ALG-2 regulates protein secretion and trafficking via interactions with MISSL and MAP1B proteins.The ALG-2 binding site in Sec31A influences the retention kinetics of Sec31A at the endoplasmic reticulum exit sites as revealed by live-cell time-lapse imaging.

P2860

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P2860

The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B

http://www.wikidata.org/entity/Q24537160

description

2005 nî lūn-bûn

@nan

2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@ast

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@en

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@nl

type

label

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@ast

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@en

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@nl

prefLabel

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@ast

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@en

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@nl

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Biochemical Journal

P1476

The penta-EF-hand protein ALG- ...... negative AAA ATPase SKD1/Vps4B

@en

P2093

Hideki Shibata

http://www.w3.org/2001/XMLSchema#string

Hidenori Suzuki

http://www.w3.org/2001/XMLSchema#string

Jiro Yasuda

http://www.w3.org/2001/XMLSchema#string

Keiichi Katoh

http://www.w3.org/2001/XMLSchema#string

Masatoshi Maki

http://www.w3.org/2001/XMLSchema#string

Takako Mizuno

http://www.w3.org/2001/XMLSchema#string

Yoshinori Terasawa

http://www.w3.org/2001/XMLSchema#string

P2860

ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking

TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes

Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner

ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner

The protein network of HIV budding

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding

The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

The penta-EF-hand protein ALG-2 interacts with a region containing PxY repeats in Alix/AIP1, which is required for the subcellular punctate distribution of the amino-terminal truncation form of Alix/AIP1

P304

677-85

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scholarly article

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3865113

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P356

10.1042/BJ20050398

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P433

Pt 3

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P478

391

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P577

2005-11-01T00:00:00Z

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P5875

7739110

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P698

16004603

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P932

1276969

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