Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.
about
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexesIdentification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activationSuppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signalingThe E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteinsAnkyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradationCOMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligasePrinciples of interleukin (IL)-6-type cytokine signalling and its regulationProlactin-induced Jak2 phosphorylation of RUSH: a key element in Jak/RUSH signalingTherapeutic targeting of Janus kinasesNuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cellsSignaling by STATsNegative regulation of cytokine signaling and immune responses by SOCS proteinsUbiquitination-mediated regulation of interferon responsesThe role of suppressors of cytokine signalling in human neoplasmsSuppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signalingSignal transducer and activator of transcription 5A/B in prostate and breast cancersLnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathwaysGlucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activationTyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation.Suppression of the interferon and NF-κB responses by severe fever with thrombocytopenia syndrome virus.Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.A bipolar clamp mechanism for activation of Jak-family protein tyrosine kinasesB56 regulatory subunit of protein phosphatase 2A mediates valproic acid-induced p300 degradationCbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction.Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.DNA damage stress and inhibition of Jak2-V617F cause its degradation and synergistically induce apoptosis through activation of GSK3βNew mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries.Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.The Jak/STAT signaling pathway is downregulated at febrile temperatures.The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction.SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.Suppression of interferon lambda signaling by SOCS-1 results in their excessive production during influenza virus infectionRegulation of cytokine receptor signaling by SOCS1.A SOCS-1 promoter variant is associated with total serum IgE levels.Suppressor of cytokine signaling 1 counteracts rhesus macaque TRIM5α-induced inhibition of human immunodeficiency virus type-1 production.FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphomaProteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signalingConditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation
P2860
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P2860
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of Jak2 through the ...... 07 and interaction with SOCS-1
@nl
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@ast
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@en
type
label
Regulation of Jak2 through the ...... 07 and interaction with SOCS-1
@nl
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@ast
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@en
prefLabel
Regulation of Jak2 through the ...... 07 and interaction with SOCS-1
@nl
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@ast
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@en
P2860
P50
P921
P3181
P1476
Regulation of Jak2 through the ...... 7 and interaction with SOCS-1.
@en
P2093
Daniela Ungureanu
Olli Silvennoinen
P2860
P304
P3181
P356
10.1128/MCB.22.10.3316-3326.2002
P407
P577
2002-05-01T00:00:00Z