The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein
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Characterization of antibodies to capsular polysaccharide antigens of Haemophilus influenzae type b and Streptococcus pneumoniae in human immune globulin intravenous preparationsEngineered IgG1-Fc--one fragment to bind them allProbing the interaction of a therapeutic flavonoid, pinostrobin with human serum albumin: multiple spectroscopic and molecular modeling investigationsSpin Diffusion Editing for Structural Fingerprints of Therapeutic AntibodiesInvestigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurementsUnderstanding the relationship between biotherapeutic protein stability and solid-liquid interfacial shear in constant region mutants of IgG1 and IgG4Surface characterization of proteins using multi-fractal property of heat-denatured aggregates.Biophysical characterization of naturally occurring titin M10 mutationsFTIR markers of methionine oxidation for early detection of oxidized protein therapeutics.Aggregation mechanism of an IgG2 and two IgG1 monoclonal antibodies at low pH: from oligomers to larger aggregates.Distinct aggregation mechanisms of monoclonal antibody under thermal and freeze-thaw stresses revealed by hydrogen exchange.Differential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils.Facile generation of heat-stable antiviral and antitoxin single domain antibodies from a semisynthetic llama library.Buffer-dependent fragmentation of a humanized full-length monoclonal antibody.Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry.Llama-derived single-domain antibodies for the detection of botulinum A neurotoxin.Aggregation of a multidomain protein: a coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stressDesign Considerations for CMOS-Integrated Hall-Effect Magnetic Bead Detectors for Biosensor Applications.Sequential events in the irreversible thermal denaturation of human brain-type creatine kinase by spectroscopic methods.Mass spectrometric analysis of intact human monoclonal antibody aggregates fractionated by size-exclusion chromatography.Characterization of the native and denatured herceptin by enzyme linked immunosorbent assay and quartz crystal microbalance using a high-affinity single chain fragment variable recombinant antibody.In vivo neutralization of botulinum neurotoxins serotype E with heavy-chain camelid antibodies (VHH).DNA unzipped under a constant force exhibits multiple metastable intermediates.Irreversible denaturation of maltodextrin glucosidase studied by differential scanning calorimetry, circular dichroism, and turbidity measurementsEndotoxin neutralization as a biomonitor for inflammatory bowel disease.Computational design of a pH-sensitive IgG binding protein.Development and evaluation of single domain antibodies for vaccinia and the L1 antigenDissecting the pretransitional conformational changes in aminoacylase I thermal denaturationWeak protein interactions and pH- and temperature-dependent aggregation of human Fc1.IgG Conformer's Binding to Amyloidogenic Aggregates.Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants.Impact of linker and conjugation chemistry on antigen binding, Fc receptor binding and thermal stability of model antibody-drug conjugatesRapid and efficient production of radiolabeled antibody conjugates using vacuum diafiltration guided by mathematical modeling.Fully automated 5-plex fluorescent immunohistochemistry with tyramide signal amplification and same species antibodies.Structural stability and heat-induced conformational change of two complement inhibitors: C4b-binding protein and factor HSingle domain antibodies for the detection of ricin using silicon photonic microring resonator arraysPhosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif.2-(2-Hydroxy-5-nitrobenzylidene)-1,3-indanedione versus Fluorescein Isothiocyanate in Interaction with Anti-hFABP Immunoglobulin G1: Fluorescence Quenching, Secondary Structure Alteration and Binding Sites LocalizationEffects of conformational ordering on protein/polyelectrolyte electrostatic complexation: ionic binding and chain stiffeningAggregation kinetics of recombinant human FVIII (rFVIII)
P2860
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P2860
The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The thermal stability of immun ...... tion of a multi-domain protein
@ast
The thermal stability of immun ...... tion of a multi-domain protein
@en
The thermal stability of immun ...... tion of a multi-domain protein
@nl
type
label
The thermal stability of immun ...... tion of a multi-domain protein
@ast
The thermal stability of immun ...... tion of a multi-domain protein
@en
The thermal stability of immun ...... tion of a multi-domain protein
@nl
prefLabel
The thermal stability of immun ...... tion of a multi-domain protein
@ast
The thermal stability of immun ...... tion of a multi-domain protein
@en
The thermal stability of immun ...... tion of a multi-domain protein
@nl
P2860
P3181
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P1476
The thermal stability of immun ...... tion of a multi-domain protein
@en
P2093
P2860
P304
P3181
P356
10.1016/S0006-3495(00)76602-1
P407
P577
2000-01-01T00:00:00Z