The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair
about
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamicsRegulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane TargetingChromatin modifications during repair of environmental exposure-induced DNA damage: a potential mechanism for stable epigenetic alterations.Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair.Orchestration of chromatin-based processes: mind the TRRAP.Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response.Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged ChromatinTranscriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.Histone H3 tails containing dimethylated lysine and adjacent phosphorylated serine modifications adopt a specific conformation during mitosis and meiosis.Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregationRadiosensitization of yeast cells by inhibition of histone h4 acetylationNMR- and circular dichroism-monitored lipid binding studies suggest a general role for the FATC domain as membrane anchor of phosphatidylinositol 3-kinase-related kinases (PIKK)Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.Heterochromatin and the DNA damage response: the need to relax.ATM protein kinase: the linchpin of cellular defenses to stress.Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA BreaksBuried territories: heterochromatic response to DNA double-strand breaks.The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains.Coactivators and general transcription factors have two distinct dynamic populations dependent on transcriptionCryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolutionThe role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks.Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells.H2AX facilitates classical non-homologous end joining at the expense of limited nucleotide loss at repair junctions.New insights into the SAGA complex from studies of the Tra1 subunit in budding and fission yeast.Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex
P2860
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P2860
The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The transcriptional histone ac ...... DNA double-strand break repair
@ast
The transcriptional histone ac ...... DNA double-strand break repair
@en
The transcriptional histone ac ...... DNA double-strand break repair
@nl
type
label
The transcriptional histone ac ...... DNA double-strand break repair
@ast
The transcriptional histone ac ...... DNA double-strand break repair
@en
The transcriptional histone ac ...... DNA double-strand break repair
@nl
prefLabel
The transcriptional histone ac ...... DNA double-strand break repair
@ast
The transcriptional histone ac ...... DNA double-strand break repair
@en
The transcriptional histone ac ...... DNA double-strand break repair
@nl
P2093
P2860
P3181
P1476
The transcriptional histone ac ...... DNA double-strand break repair
@en
P2093
Céline Baldeyron
Dora Papadopoulo
Flavie Robert
Jean-Yves Masson
Làszlò Tora
Sara Hardy
Zdenko Herceg
P2860
P304
P3181
P356
10.1128/MCB.26.2.402-412.2006
P407
P50
P577
2006-01-01T00:00:00Z