Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1.
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Surgical interventions for primary congenital glaucomaCancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient airLocalization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region.Digenic inheritance of early-onset glaucoma: CYP1B1, a potential modifier geneIdentification of a single ancestral CYP1B1 mutation in Slovak Gypsies (Roms) affected with primary congenital glaucomaCancer Activation and Polymorphisms of Human Cytochrome P450 1B1CYP1B1-mediated Pathobiology of Primary Congenital GlaucomaOcular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic dispositionPolymorphisms in the human cytochrome P450 and arylamine N-acetyltransferase: susceptibility to head and neck cancersGenetic, Biochemical and Clinical Insights into Primary Congenital GlaucomaDisease-causing mutations in proteins: structural analysis of the CYP1B1 mutations causing primary congenital glaucoma in humans.Mutations in the CYP1B1 gene may contribute to juvenile-onset open-angle glaucomaIdentification of four novel cytochrome P4501B1 mutations (p.I94X, p.H279D, p.Q340H, and p.K433K) in primary congenital glaucoma patients.Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia.Glaucoma genetics, present and future.Novel TIGR/MYOC mutations in families with juvenile onset primary open angle glaucoma.Structural and functional insights into polymorphic enzymes of cytochrome P450 2C8.Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8, CRYGC, PAX6 and CYP1B1.Mutational spectrum of the CYP1B1 gene in Pakistani patients with primary congenital glaucoma: novel variants and genotype-phenotype correlations.Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer.Screening of CYP1B1 and MYOC in Moroccan families with primary congenital glaucoma: three novel mutations in CYP1B1.Molecular genetics of primary congenital glaucoma.Roles of cytochrome p450 in development.CYP1B1 C4326G polymorphism and susceptibility to cervical cancer in Chinese Han women.Multiple hits during early embryonic development: digenic diseases and holoprosencephalySequence analysis of MYOC and CYP1B1 in a Chinese pedigree of primary open-angle glaucoma.Carrier frequency of CYP1B1 mutations in the United States (an American Ophthalmological Society thesis).Contribution of GLC3A locus to Primary Congenital Glaucoma in Pakistani population.Pharmacogenetics of the major polymorphic metabolizing enzymes.CYP1B1 copy number variation is not a major contributor to primary congenital glaucomaAssociation between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: a meta-analysisMolecular characterisation of congenital glaucoma in a consanguineous Canadian community: a step towards preventing glaucoma related blindness.CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma.Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation.Cytochrome P450 1B1 and Primary Congenital GlaucomaGlaucoma in iran and contributions of studies in iran to the understanding of the etiology of glaucoma.Phenotype of cytochrome P4501B1 gene (CYP1B1) mutations in Japanese patients with primary congenital glaucoma.Pharmacogenomics and breast cancer.Genotype and phenotype correlations in congenital glaucoma.Dietary phytoestrogen intake is associated with reduced colorectal cancer risk.
P2860
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P2860
Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Sequence analysis and homology ...... ructures of cytochrome P4501B1
@nl
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@ast
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@en
type
label
Sequence analysis and homology ...... ructures of cytochrome P4501B1
@nl
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@ast
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@en
prefLabel
Sequence analysis and homology ...... ructures of cytochrome P4501B1
@nl
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@ast
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@en
P2093
P2860
P3181
P356
P1476
Sequence analysis and homology ...... uctures of cytochrome P4501B1.
@en
P2093
A N Akarsu
L Chevrette
M Barsoum-Homsy
M Coca-Prados
M E Turacli
P2860
P304
P3181
P356
10.1086/301764
P407
P577
1998-03-01T00:00:00Z