Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay.
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Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assemblyA noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defectsRegulation of mRNA export by the PI3 kinase/AKT signal transduction pathway.Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex componentsDifferential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins.The DEAD-box RNA helicase-like Utp25 is an SSU processome component.Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complexEukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporationInhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIIISelective pharmacological targeting of a DEAD box RNA helicase.The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR.The two eIF4A helicases in Trypanosoma brucei are functionally distinct.An alternative branch of the nonsense-mediated decay pathwayThe N-terminal Domain of Escherichia coli Assimilatory NADPH-Sulfite Reductase Hemoprotein Is an Oligomerization Domain That Mediates Holoenzyme Assembly.Perispeckles are major assembly sites for the exon junction core complex.Introns play an essential role in splicing-dependent formation of the exon junction complex.Premature Termination Codons Are Recognized in the Nucleus in A Reading-Frame Dependent MannerPowering through ribosome assembly.Structural aspects of RNA helicases in eukaryotic mRNA decay.Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1.Inhibitors of translation initiation as cancer therapeutics.Regulation of nonsense-mediated mRNA decay.The Ded1/DDX3 subfamily of DEAD-box RNA helicases.The exon junction complex: a lifelong guardian of mRNA fate.FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis.Flexibility in the site of exon junction complex deposition revealed by functional group and RNA secondary structure alterations in the splicing substrate.MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis.Dynamic behavior of Arabidopsis eIF4A-III, putative core protein of exon junction complex: fast relocation to nucleolus and splicing speckles under hypoxia.Structure of Dicer and mechanistic implications for RNAi.Localization of RNA and translation in the mammalian oocyte and embryo.UPF1-like helicase grip on nucleic acids dictates processivity
P2860
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P2860
Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mutational analysis of human e ...... d nonsense-mediated mRNA decay
@nl
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@ast
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@en
type
label
Mutational analysis of human e ...... d nonsense-mediated mRNA decay
@nl
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@ast
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@en
prefLabel
Mutational analysis of human e ...... d nonsense-mediated mRNA decay
@nl
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@ast
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@en
P2093
P2860
P356
P1433
P1476
Mutational analysis of human e ...... nonsense-mediated mRNA decay.
@en
P2093
M Elizabeth Stroupe
Melissa J Moore
Thomas Ø Tange
Toshiharu Shibuya
P2860
P304
P356
10.1261/RNA.2190706
P407
P577
2006-03-01T00:00:00Z