The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 - Wikidata - awgldk - TriplyDB

The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1

The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1

http://www.wikidata.org/entity/Q24550350

about

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis Stress-induced decrease in TRAF2 stability is mediated by Siah2 Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development.Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes.The ubiquitin ligase Siah2 and the hypoxia response.Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue.Normal p53 function in primary cells deficient for Siah genes.Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.Involvement of seven in absentia homolog-1 in ethanol-induced apoptosis in neural crest cells The Ets factor Spi-B is a direct critical target of the coactivator OBF-1 A binding motif for Siah ubiquitin ligase.Generation and analysis of Siah2 mutant mice.On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants.Herpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation.Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses.B cells, E2A, and aging.Transcriptional networks in developing and mature B cells.E3 ubiquitin ligases SIAH1/2 regulate hypoxia-inducible factor-1 (HIF-1)-mediated Th17 cell differentiation.PKC phosphorylation regulates mGluR5 trafficking by enhancing binding of Siah-1A.Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter A C-terminal acidic domain regulates degradation of the transcriptional coactivator Bob1.SIAH-1 interacts with the Kaposi's sarcoma-associated herpesvirus-encoded ORF45 protein and promotes its ubiquitylation and proteasomal degradation.Two modes of degradation of the tramtrack transcription factors by Siah homologues.E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1.Interaction of the B cell-specific transcriptional coactivator OCA-B and galectin-1 and a possible role in regulating BCR-mediated B cell proliferation.Myosin light chain 1 atrial isoform (MLC1A) is expressed in pre-B cells under control of the BOB.1/OBF.1 coactivator Expression of the aldehyde dehydrogenase 2-like gene is controlled by BOB.1/OBF.1 in B lymphocytes.B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice.Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells.The E3 ubiquitin ligase Siah-1 suppresses avian reovirus infection by targeting p10 for degradation.Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma.

P2860

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P2860

The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1

http://www.wikidata.org/entity/Q24550350

description

2001 nî lūn-bûn

@nan

2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@ast

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@en

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@nl

type

label

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@ast

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@en

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@nl

prefLabel

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@ast

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@en

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@nl

P1433

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P2860

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Q24550350-376BF4B0-98EC-4A3B-9212-7C3A7610C3E8

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Q24550350-87A95FFB-F208-4541-8257-1524B1D024A9

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Q24550350-42DE63AA-A1D0-472B-974D-8F02E5C8986B

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P932

Q24550350-9AF2F6A1-8614-4014-BA59-C76BDACD2665

P356

P1433

The EMBO Journal

P1476

The RING finger protein Siah-1 ...... nscriptional coactivator OBF-1

@en

P2093

B A Bartholdy

http://www.w3.org/2001/XMLSchema#string

G Matthias

http://www.w3.org/2001/XMLSchema#string

J W Newell

http://www.w3.org/2001/XMLSchema#string

P Matthias

http://www.w3.org/2001/XMLSchema#string

R Tiedt

http://www.w3.org/2001/XMLSchema#string

P2860

hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

Characterization of human homologs of the Drosophila seven in absentia (sina) gene

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Coactivation by OCA-B: definition of critical regions and synergism with general cofactors.

Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA.

Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins

Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface

P304

4143-52

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/EMBOJ/20.15.4143

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P407

P433

15

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P478

20

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P577

2001-08-01T00:00:00Z

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P5875

24536633

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P698

11483517

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P932

149178

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