Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex - Wikidata - awgldk - TriplyDB

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

http://www.wikidata.org/entity/Q24554281

about

Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway MLK3 Signaling in Cancer Invasion Cytosolic Hsp60 is involved in the NF-kappaB-dependent survival of cancer cells via IKK regulation Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain.Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines.Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm.TRAF2-MLK3 interaction is essential for TNF-alpha-induced MLK3 activation.Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades.An enigmatic tail of CD28 signaling.Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders T lymphocyte activation--an inside overview.Mixed-lineage kinase control of JNK and p38 MAPK pathways.Decrement of miR-199a-5p contributes to the tumorigenesis of bladder urothelial carcinoma by regulating MLK3/NF-κB pathway Unravelling druggable signalling networks that control F508del-CFTR proteostasis Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6.Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells.Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells.Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death.Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex.p21-activated kinase 1 activates the nuclear factor kappa B (NF-kappa B)-inducing kinase-Ikappa B kinases NF-kappa B pathway and proinflammatory cytokines in Helicobacter pylori infection.Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways.Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-kappaB activation.TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells.

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Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

http://www.wikidata.org/entity/Q24554281

description

2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@ast

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@en

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@nl

type

label

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@ast

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@en

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@nl

prefLabel

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@ast

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@en

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@nl

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MCB.20.7.2556-2568.2000

P1433

Molecular and Cellular Biology

P1476

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

@en

P2093

C Scheidereit

http://www.w3.org/2001/XMLSchema#string

I Wing-Lan Leung

http://www.w3.org/2001/XMLSchema#string

M L Schmitz

http://www.w3.org/2001/XMLSchema#string

N Lassam

http://www.w3.org/2001/XMLSchema#string

O Dienz

http://www.w3.org/2001/XMLSchema#string

S P Hehner

http://www.w3.org/2001/XMLSchema#string

T G Hofmann

http://www.w3.org/2001/XMLSchema#string

W Dröge

http://www.w3.org/2001/XMLSchema#string

P2860

Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2

The NF-kappa B and I kappa B proteins: new discoveries and insights

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain

Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

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2556-2568

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scholarly article

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1493834

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10.1128/MCB.20.7.2556-2568.2000

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P433

7

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20

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Alexey Ushmorov

P577

2000-04-01T00:00:00Z

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12602976

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10713178

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85472

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