Chromosomal variation in neurons of the developing and adult mammalian nervous system
about
Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansionVery small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristicsAneuploid neurons are functionally active and integrated into brain circuitryExtrachromosomal microDNAs and chromosomal microdeletions in normal tissuesWhen 2+2=5: the origins and fates of aneuploid and tetraploid cellsEthanol induces cell-cycle activity and reduces stem cell diversity to alter both regenerative capacity and differentiation potential of cerebral cortical neuroepithelial precursors.Horizontal Cells, the Odd Ones Out in the Retina, Give Insights into Development and DiseaseAneuploidy in stem cellsDifferent Facets of Copy Number Changes: Permanent, Transient, and AdaptiveSomatic mosaicism in the human genomeMurine and human very small embryonic-like cells: a perspectiveSomatic mutations in aging, cancer and neurodegenerationA tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazoleHeterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genomeCauses of genome instability: the effect of low dose chemical exposures in modern societyAllocating structure to function: the strong links between neuroplasticity and natural selection.The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning.Single neuron transcriptome analysis can reveal more than cell type classification: Does it matter if every neuron is unique?Novel subcellular localization of the DNA helicase Twinkle at the kinetochore complex during mitosis in neuronal-like progenitor cells.Mosaic copy number variation in human neuronsSomatic alpha-synuclein mutations in Parkinson's disease: hypothesis and preliminary data.Aneuploidy and confined chromosomal mosaicism in the developing human brain.Neuronal aneuploidy in health and disease: a cytomic approach to understand the molecular individuality of neurons.Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: requirement for tau and APP.Neuronal DNA content variation (DCV) with regional and individual differences in the human brainSomatic mutations, genome mosaicism, cancer and aging.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brainIn search of principles for a Theory of Organisms.Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation.Selective cell death of hyperploid neurons in Alzheimer's disease.Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidyMassively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells.LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?Passage number is a major contributor to genomic structural variations in mouse iPSCs.Single cell sequencing reveals low levels of aneuploidy across mammalian tissues.The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation.Mechanisms of aneuploidy.Is synaesthesia an X-linked dominant trait with lethality in males?Three-dimensional genome architecture: players and mechanisms.
P2860
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P2860
Chromosomal variation in neurons of the developing and adult mammalian nervous system
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@ast
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@en
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@nl
type
label
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@ast
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@en
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@nl
prefLabel
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@ast
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@en
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@nl
P2093
P2860
P3181
P356
P1476
Chromosomal variation in neurons of the developing and adult mammalian nervous system
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.231487398
P407
P577
2001-11-06T00:00:00Z