Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function - Wikidata - awgldk - TriplyDB

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function

http://www.wikidata.org/entity/Q24558690

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Dual specificity of Langerin to sulfated and mannosylated glycans via a single C-type carbohydrate recognition domain The continuing challenges of leprosy The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells Trimeric Structure of Langerin Polymorphisms in human langerin affect stability and sugar binding activity MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo.CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells Ontogenic, Phenotypic, and Functional Characterization of XCR1(+) Dendritic Cells Leads to a Consistent Classification of Intestinal Dendritic Cells Based on the Expression of XCR1 and SIRPα Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells.Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis.A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles.Identification of a novel population of Langerin+ dendritic cells.Lack of microRNA miR-150 reduces the capacity of epidermal Langerhans cell cross-presentation Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile.Carbohydrate recognition systems in autoimmunity.DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance.Human Immunodeficiency Virus Immune Cell Receptors, Coreceptors, and Cofactors: Implications for Prevention and Treatment.Deletion of microRNA miR-223 increases Langerhans cell cross-presentation.Resident and "inflammatory" dendritic cells in human skin.Insights into Langerhans cell function from Langerhans cell ablation models.The Janus face of dendritic cells in cancer.Suppression of the CD8 T cell response by human papillomavirus type 16 E7 occurs in Langerhans cell-depleted mice.Characteristics and functions of murine cutaneous dendritic cells: a synopsis of recent developments.Thymus and aging: morphological, radiological, and functional overview.BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.Revisiting the tolerogenicity of epidermal Langerhans cells.Disentangling the complexity of the skin dendritic cell network.Identification of three distinct subsets of migrating dendritic cells from oral mucosa within the regional lymph nodes.Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species?Flk2+ myeloid progenitors are the main source of Langerhans cells.Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells.Intestinal Langerhans cell histiocytosis-like lesion in an adult presented with diverticulitis: a reactive or neoplastic condition?Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells.

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Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function

http://www.wikidata.org/entity/Q24558690

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2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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Disruption of the langerin/CD2 ...... ss of Langerhans cell function

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Disruption of the langerin/CD2 ...... ss of Langerhans cell function

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Disruption of the langerin/CD2 ...... ss of Langerhans cell function

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Disruption of the langerin/CD2 ...... ss of Langerhans cell function

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MCB.25.1.88-99.2005

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Molecular and Cellular Biology

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Disruption of the langerin/CD2 ...... ss of Langerhans cell function

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Edgar Badell

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Geneviève Milon

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Hella Stössel

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Isabelle Coste

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Joanne L Pooley

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Ken Shortman

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Olivia Gresser

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Patrice Douillard

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Sem Saeland

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Smina Aït-Yahia

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P2860

Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules

Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates

Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells.

Dendritic cells and the control of immunity

Langerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells

Diversity of receptors binding HIV on dendritic cell subsets

Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues

Mycobacteria target DC-SIGN to suppress dendritic cell function

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

Dendritic cells: specialized and regulated antigen processing machines

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88-99

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1

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25

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Bernard Malissen

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Adrien Kissenpfennig

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2005-01-01T00:00:00Z

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15601833

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