Fibril in senile systemic amyloidosis is derived from normal transthyretin - Wikidata - awgldk - TriplyDB

Fibril in senile systemic amyloidosis is derived from normal transthyretin

Fibril in senile systemic amyloidosis is derived from normal transthyretin

http://www.wikidata.org/entity/Q24558717

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The 8 and 5 kDa fragments of plasma gelsolin form amyloid fibrils by a nucleated polymerization mechanism, while the 68 kDa fragment is not amyloidogenic Binding of perlecan to transthyretin in vitro Amyloid heart disease. New frontiers and insights in pathophysiology, diagnosis, and management.Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis Toward Optimization of the Linker Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies †Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies †Amyloidogenic Potential of Transthyretin Variants: INSIGHTS FROM STRUCTURAL AND COMPUTATIONAL ANALYSES Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors Structural evidence for asymmetric ligand binding to transthyretin Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR)Evolving landscape in the management of transthyretin amyloidosis Beyond genetic factors in familial amyloidotic polyneuropathy: protein glycation and the loss of fibrinogen's chaperone activity The proteome response to amyloid protein expression in vivo Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic?Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretin The sour side of neurodegenerative disorders: the effects of protein glycation.Is Transthyretin a Regulator of Ubc9 SUMOylation?Transthyretin variants with improved inhibition of β-amyloid aggregation.A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin.Identification and quantitative analysis of human transthyretin variants in human serum by Fourier transform ion-cyclotron resonance mass spectrometry.Amyloidosis and the respiratory tract Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.Pathologic changes and glucose homeostasis according to expression of human islet amyloid polypeptide in type 2 diabetic patients The relative amounts of plasma transthyretin forms in familial transthyretin amyloidosis: a quantitative analysis by Fourier transform ion-cyclotron resonance mass spectrometry.Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy.

P2860

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P2860

Fibril in senile systemic amyloidosis is derived from normal transthyretin

http://www.wikidata.org/entity/Q24558717

description

1990 nî lūn-bûn

@nan

1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1990 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1990年の論文

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1990年論文

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1990年論文

@zh-hant

1990年論文

@zh-hk

1990年論文

@zh-mo

1990年論文

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1990年论文

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name

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@ast

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@en

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@nl

type

label

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@ast

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@en

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@nl

prefLabel

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@ast

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@en

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Fibril in senile systemic amyloidosis is derived from normal transthyretin

@en

P2093

B Johansson

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G G Cornwell

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K Sletten

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P Westermark

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P2860

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma

Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A

The complete amino-acid sequence of non-immunoglobulin amyloid fibril protein AS in rheumatoid arthritis

Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy

Substrate specificity of a proteolytic enzyme isolated from a mutant of Pseudomonas fragi.

Characterization of a transthyretin (prealbumin) variant associated with familial amyloidotic polyneuropathy type II (Indiana/Swiss).

Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).

Identification of a new hereditary amyloidosis prealbumin variant, Tyr-77, and detection of the gene by DNA analysis.

Biochemical and molecular genetic characterization of a new variant prealbumin associated with hereditary amyloidosis.

Senile systemic amyloidosis.

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scholarly article

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2230441

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10.1073/PNAS.87.7.2843

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7

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87

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20834679

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2320592

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53787

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