A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer
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Dysregulation of miR-15a and miR-214 in human pancreatic cancerThe candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).Keep-ING balance: tumor suppression by epigenetic regulationING4 Mediates Crosstalk between Histone H3 K4 Trimethylation and H3 Acetylation to Attenuate Cellular TransformationFunctional impact of cancer-associated mutations in the tumor suppressor protein ING4Crystal Structure of Inhibitor of Growth 4 (ING4) Dimerization Domain Reveals Functional Organization of ING Family of Chromatin-binding ProteinsING proteins as potential anticancer drug targets.Cancer epigenetics: a brief review.Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.Downregulated inhibitor of growth 3 (ING3) expression during colorectal carcinogenesis.The ING gene family in the regulation of cell growth and tumorigenesis.A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis.Expression of inhibitor of growth 4 by HSV1716 improves oncolytic potency and enhances efficacy.Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancerNovel splice variants of ING4 and their possible roles in the regulation of cell growth and motility.Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cellsDeletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer.ING4 enhances paclitaxel's effect on colorectal cancer growth in vitro and in vivoDownregulation of inhibitor of growth 3 is correlated with tumorigenesis and progression of hepatocellular carcinomaImpact of deleterious passenger mutations on cancer progression.Reduced expression and prognostic implication of inhibitor of growth 4 in human osteosarcoma.The MYST family of histone acetyltransferases and their intimate links to cancer.Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genesCombinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer.Mechanism of Histone H3K4me3 Recognition by the Plant Homeodomain of Inhibitor of Growth 3.Down-regulation of ING4 is associated with initiation and progression of lung cancer.Reduced expression and novel splice variants of ING4 in human gastric adenocarcinomaTumor suppressor ING4 inhibits estrogen receptor activity in breast cancer cells.A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients.Inhibitor of growth-4 mediates chromatin modification and has a suppressive effect on tumorigenesis and innate immunity.Regulation of p53 by ING family members in suppression of tumor initiation and progression.Cancer may be a pathway to cell survival under persistent hypoxia and elevated ROS: a model for solid-cancer initiation and early development.Inhibitor of growth-4 is a potential target for cancer therapy.Adenovirus-mediated co-expression of ING4 and PTEN cooperatively enhances their antitumor activity in human hepatocellular carcinoma cells.Overexpression of Inhibitor of Growth 4 Enhances Radiosensitivity in Non-Small Cell Lung Cancer Cell Line SPC-A1.Synergistic tumor suppression by adenovirus-mediated ING4/PTEN double gene therapy for gastric cancer.INGs are potential drug targets for cancer.Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers.ARID1B, a member of the human SWI/SNF chromatin remodeling complex, exhibits tumour-suppressor activities in pancreatic cancer cell lines.
P2860
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P2860
A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer
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2004 nî lūn-bûn
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2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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A screen for genes that suppre ...... uppressor gene in human cancer
@ast
A screen for genes that suppre ...... uppressor gene in human cancer
@en
A screen for genes that suppre ...... uppressor gene in human cancer
@nl
type
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A screen for genes that suppre ...... uppressor gene in human cancer
@ast
A screen for genes that suppre ...... uppressor gene in human cancer
@en
A screen for genes that suppre ...... uppressor gene in human cancer
@nl
prefLabel
A screen for genes that suppre ...... uppressor gene in human cancer
@ast
A screen for genes that suppre ...... uppressor gene in human cancer
@en
A screen for genes that suppre ...... uppressor gene in human cancer
@nl
P2093
P2860
P3181
P356
P1476
A screen for genes that suppre ...... uppressor gene in human cancer
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P2093
J Michael Bishop
Joe W Gray
P2860
P304
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P356
10.1073/PNAS.0407158101
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P577
2004-11-16T00:00:00Z