Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome
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Nedd4-2 and the regulation of epithelial sodium transportRole of the UPS in Liddle syndromeLatent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinasesIdentification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligandsRegulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expressionAn aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complexNedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approachPermeability properties of ENaC selectivity filter mutantsEpithelial Na(+) channel regulation by cytoplasmic and extracellular factorsThe role of the ENaC-regulatory complex in aldosterone-mediated sodium transportOrganization of the ENaC-regulatory machinerySna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sortingYeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseasesFunctional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.Epithelial sodium channel regulated by aldosterone-induced protein sgk.Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the beta-subunit of the amiloride-sensitive epithelial sodium channelGenetic mapping of a new heart rate QTL on chromosome 8 of spontaneously hypertensive rats.Short-term regulation of organic anion transportersFunctional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.Massive losses of taste receptor genes in toothed and baleen whales.Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.Point mutations in alpha bENaC regulate channel gating, ion selectivity, and sensitivity to amiloride.Ubiquitin metabolism affects cellular response to volatile anesthetics in yeast.Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel.Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2.Ion channel associated diseases: overview of molecular mechanismsERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage.Molecular mechanism of constitutive endocytosis of Acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death.The WNKs: atypical protein kinases with pleiotropic actions.Overexpression of the epithelial Na+ channel gamma subunit in collecting duct cells: interactions of Liddle's mutations and steroids on expression and function.Genetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies.Regulation of the epithelial sodium channel by accessory proteinsNeural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.ENaCs and ASICs as therapeutic targets.
P2860
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P2860
Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
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name
Identification of a PY motif i ...... ation found in Liddle syndrome
@ast
Identification of a PY motif i ...... ation found in Liddle syndrome
@en
Identification of a PY motif i ...... ation found in Liddle syndrome
@nl
type
label
Identification of a PY motif i ...... ation found in Liddle syndrome
@ast
Identification of a PY motif i ...... ation found in Liddle syndrome
@en
Identification of a PY motif i ...... ation found in Liddle syndrome
@nl
prefLabel
Identification of a PY motif i ...... ation found in Liddle syndrome
@ast
Identification of a PY motif i ...... ation found in Liddle syndrome
@en
Identification of a PY motif i ...... ation found in Liddle syndrome
@nl
P2093
P2860
P1433
P1476
Identification of a PY motif i ...... ation found in Liddle syndrome
@en
P2093
P2860
P304
P407
P577
1996-05-15T00:00:00Z