Pauling and Corey's alpha-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid disease
about
A Chronic Fatigue Syndrome - related proteome in human cerebrospinal fluid.The Ramachandran Number: An Order Parameter for Protein GeometryThe drive to life on wet and icy worldsFunctional capabilities of the earliest peptides and the emergence of lifeAn exhaustive survey of regular peptide conformations using a new metric for backbone handedness (h)Structural classification of toxic amyloid oligomersPotentially amyloidogenic conformational intermediates populate the unfolding landscape of transthyretin: insights from molecular dynamics simulations.Structural and dynamic properties of the human prion protein.Quantum mechanical studies on model alpha-pleated sheets.Prion and water: tight and dynamical hydration sites have a key role in structural stability.Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers.Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases.Simulation of the β- to α-sheet transition results in a twisted sheet for antiparallel and an α-nanotube for parallel strands: implications for amyloid formation.Diverse effects on the native β-sheet of the human prion protein due to disease-associated mutations.Initial conformational changes of human transthyretin under partially denaturing conditionsAggregation drives "misfolding" in protein amyloid fiber formation.The elusive nature and diagnostics of misfolded Aβ oligomers.Molecular dynamics simulation suggests possible interaction patterns at early steps of beta2-microglobulin aggregation.Contact-induced structure transformation in transmembrane prion propagation.Quantitative evaluation of positive ϕ angle propensity in flexible regions of proteins from three-bond J couplingsInsights into Unfolded Proteins from the Intrinsic ϕ/ψ Propensities of the AAXAA Host-Guest Series.Protein aggregation in silico.Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence.Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.Mechanisms of amyloid fibril formation--focus on domain-swapping.Understanding the complex mechanisms of β2-microglobulin amyloid assembly.Geometrical principles of homomeric β-barrels and β-helices: Application to modeling amyloid protofilaments.Structural and functional diversity among amyloid proteins: Agents of disease, building blocks of biology, and implications for molecular engineering.Insights from molecular dynamics simulations for computational protein design.Intrinsic Free Energy of the Conformational Transition of the KcsA Signature Peptide from Conducting to Nonconducting StateDesigned α-sheet peptides suppress amyloid formation in Staphylococcus aureus biofilms.Few Ramachandran Angle Changes Provide Interaction Strength Increase in Aβ42 versus Aβ40 Amyloid FibrilsAromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathwaysChemical and Physical Variability in Structural Isomers of an l/d α-Sheet Peptide Designed To Inhibit Amyloidogenesis.Possible Existence of α-Sheets in the Amyloid Fibrils Formed by a TTR105-115 Mutant.Interplay between the hydrophobic effect and dipole interactions in peptide aggregation at interfaces.Flexible docking of an amyloid-forming peptide from beta(2)-microglobulinThe Role of α-sheet in Amyloid Oligomer Aggregation and Toxicity
P2860
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P2860
Pauling and Corey's alpha-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid disease
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@ast
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@en
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@nl
type
label
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@ast
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@en
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@nl
prefLabel
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@ast
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@en
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@nl
P2093
P2860
P3181
P356
P1476
Pauling and Corey's alpha-plea ...... ntermediate in amyloid disease
@en
P2093
Darwin O V Alonso
Mari L DeMarco
Roger S Armen
P2860
P304
P3181
P356
10.1073/PNAS.0401781101
P407
P577
2004-08-10T00:00:00Z