Overexpression of human loricrin in transgenic mice produces a normal phenotype - Wikidata - awgldk - TriplyDB

Overexpression of human loricrin in transgenic mice produces a normal phenotype

Overexpression of human loricrin in transgenic mice produces a normal phenotype

http://www.wikidata.org/entity/Q24564298

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cDNA cloning and characterization of sciellin, a LIM domain protein of the keratinocyte cornified envelope The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' family Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope The Proximal Promoter of the Human Transglutaminase 3 Gene Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6 The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression.Loricrin - an overview.Expression of wild-type, but not mutant, loricrin causes programmed cell death in HaCaT keratinocytes.Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma.An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex.Localization of sphingomyelin during the development of dorsal and tail epidermis of mice.Analysis of the expression pattern of involucrin in human scalp skin and hair follicles: hair cycle-associated alterations.Loss of spr1 expression measurable by quantitative RT-PCR in human bronchogenic carcinoma cell lines.Regulation of forestomach-specific expression of the murine adenosine deaminase gene.Biochemical evidence that small proline-rich proteins and trichohyalin function in epithelia by modulation of the biomechanical properties of their cornified cell envelopes.

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P2860

Overexpression of human loricrin in transgenic mice produces a normal phenotype

http://www.wikidata.org/entity/Q24564298

description

1993 nî lūn-bûn

@nan

1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1993 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1993年の論文

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1993年論文

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1993年論文

@zh-hant

1993年論文

@zh-hk

1993年論文

@zh-mo

1993年論文

@zh-tw

1993年论文

@wuu

name

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@ast

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@en

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@nl

type

label

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@ast

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@en

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@nl

prefLabel

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@ast

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@en

Overexpression of human loricrin in transgenic mice produces a normal phenotype

@nl

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PNAS.90.22.10754

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Proceedings of the National Academy of Sciences of the United States of America

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Overexpression of human loricrin in transgenic mice produces a normal phenotype

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K Yoneda

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P M Steinert

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P2860

Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins

Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions

Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope

The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids

Extensive size polymorphism of the human keratin 10 chain resides in the C-terminal V2 subdomain due to variable numbers and sizes of glycine loops

The human loricrin gene

Identification of a major keratinocyte cell envelope protein, loricrin

The two size alleles of human keratin 1 are due to a deletion in the glycine-rich carboxyl-terminal V2 subdomain.

Expression of epidermal keratins and filaggrin during human fetal skin development

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