Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport
about
TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transportMAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membraneThe alpha- and beta'-COP WD40 domains mediate cargo-selective interactions with distinct di-lysine motifs.The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.Identification and localization of ERD2 in the malaria parasite Plasmodium falciparum: separation from sites of sphingomyelin synthesis and implications for organization of the GolgiMutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infectionQuantitative ER <--> Golgi transport kinetics and protein separation upon Golgi exit revealed by vesicular integral membrane protein 36 dynamics in live cells.Receptor for retrograde transport in the apicomplexan parasite Toxoplasma gondiiCystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors involved in vesicle traffickingProtease-associated cellular networks in malaria parasite Plasmodium falciparum.KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex.Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice.Dynamics of the endoplasmic reticulum and golgi apparatus during early sea urchin developmentA molecular specificity code for the three mammalian KDEL receptors.Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity.Drosophila KDEL receptor function in the embryonic salivary gland and epidermis.Prohibitin: A Novel Molecular Player in KDEL Receptor Signalling.Modulation of intracellular transport by transported proteins: insight from regulation of COPI-mediated transport.The KDEL receptor couples to Gαq/11 to activate Src kinases and regulate transport through the GolgiLocalization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells.Retrograde transport of Golgi-localized proteins to the ER.Two separate signals act independently to localize a yeast late Golgi membrane protein through a combination of retrieval and retentionThe Arabidopsis endoplasmic reticulum retention receptor functions in yeastE5 oncoprotein retained in the endoplasmic reticulum/cis Golgi still induces PDGF receptor autophosphorylation but does not transform cellsProtein recycling from the Golgi apparatus to the endoplasmic reticulum in plants and its minor contribution to calreticulin retention.Is the 6 kDa tobacco etch viral protein a bona fide ERES marker?The differential palmitoylation states of N-Ras and H-Ras determine their distinct Golgi subcompartment localizations.Investigations of human myosin VI targeting using optogenetically controlled cargo loading.Carboxylesterases in lipid metabolism: from mouse to human.The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum.The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus.Retrieval of TGN proteins from the cell surface requires endosomal acidification.Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER-->Golgi transport in yeastTransport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase.Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: studies with cholera toxin in Vero cells.Retrieval of HDEL proteins is required for growth of yeast cells.Cab45 is required for Ca(2+)-dependent secretory cargo sorting at the trans-Golgi networkKDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p.Saturation of the endoplasmic reticulum retention machinery reveals anterograde bulk flow
P2860
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P2860
Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Mutational analysis of the hum ...... nding and retrograde transport
@ast
Mutational analysis of the hum ...... nding and retrograde transport
@en
Mutational analysis of the hum ...... nding and retrograde transport
@nl
type
label
Mutational analysis of the hum ...... nding and retrograde transport
@ast
Mutational analysis of the hum ...... nding and retrograde transport
@en
Mutational analysis of the hum ...... nding and retrograde transport
@nl
prefLabel
Mutational analysis of the hum ...... nding and retrograde transport
@ast
Mutational analysis of the hum ...... nding and retrograde transport
@en
Mutational analysis of the hum ...... nding and retrograde transport
@nl
P2093
P2860
P921
P1433
P1476
Mutational analysis of the hum ...... nding and retrograde transport
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1993.TB05943.X
P407
P577
1993-07-01T00:00:00Z