The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
about
p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosisThe amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processingIdentification of G1 kinase activity for cdk6, a novel cyclin D partnerRaf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulationNegative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma proteinFunctions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteinsThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid systemThe product of the EMS1 gene, amplified and overexpressed in human carcinomas, is homologous to a v-src substrate and is located in cell-substratum contact sitesE2F activity is regulated by cell cycle-dependent changes in subcellular localizationE2F-4 switches from p130 to p107 and pRB in response to cell cycle reentryDifferent roles for cyclins D1 and E in regulation of the G1-to-S transitionIn vivo association of E2F and DP family proteinsThe structure of CDK4/cyclin D3 has implications for models of CDK activationStructures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle controlDifferential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivoPhosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cellsActopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinaseCyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylationRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesA Strategy for Direct Chemical Activation of the Retinoblastoma ProteinOverexpression of CDC2/CyclinB1 in gliomas, and CDC2 depletion inhibits proliferation of human glioma cells in vitro and in vivoThe paramyxovirus simian virus 5 V protein slows progression of the cell cycle.14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasisThe H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in DrosophilaLack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain bindingGene network landscape of the ciliate Tetrahymena thermophila.Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor.Cumulative effect of phosphorylation of pRB on regulation of E2F activity.Tumor promotion by caspase-resistant retinoblastoma proteinGlobal discovery of high-NaCl-induced changes of protein phosphorylationDeficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylationStudy of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells.Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression.Clefts, grooves, and (small) pockets: the structure of the retinoblastoma tumor suppressor in complex with its cellular target E2F unveiled.
P2860
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P2860
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@ast
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@en
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@nl
type
label
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@ast
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@en
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@nl
prefLabel
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@ast
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@en
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@nl
P2093
P2860
P1433
P1476
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2
@en
P2093
C W Anderson
D R Marshak
K J Buchkovich
P2860
P304
P407
P577
1991-12-01T00:00:00Z