Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance - Wikidata - awgldk - TriplyDB

Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance

Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance

http://www.wikidata.org/entity/Q24564647

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Exploiting Genetic Interference for Antiviral Therapy Gene transfer in humans using a conditionally replicating lentiviral vector HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.Targeted infection of HIV-1 Env expressing cells by HIV(CD4/CXCR4) vectors reveals a potential new rationale for HIV-1 mediated down-modulation of CD4 Bone Marrow Gene Therapy for HIV/AIDS Lipid nanoparticles as carriers for RNAi against viral infections: current status and future perspectives HIV-1 reverse transcription Engineering T Cells to Functionally Cure HIV-1 Infection Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.Computational models of HIV-1 resistance to gene therapy elucidate therapy design principles HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse model Newly designed six-membered azasugar nucleotide-containing phosphorothioate oligonucleotides as potent human immunodeficiency virus type 1 inhibitors.Rev-free HIV-1 gene delivery system for targeting Rev-RRE-Crm1 nucleocytoplasmic RNA transport pathway RNAi and small interfering RNAs in human disease therapeutic applications.Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration.Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV Regulation of Antisense Transcription by NuA4 Histone Acetyltransferase and Other Chromatin Regulatory Factors Genetic therapies against HIV.RNA-based gene therapy for the treatment and prevention of HIV: from bench to bedside.Novel cell and gene therapies for HIV.Design and development of antisense drugs.Potential mechanisms for cell-based gene therapy to treat HIV/AIDS.Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays.Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.A spatially varying two-sample recombinant coalescent, with applications to HIV escape response.A preliminary step of a novel strategy in suicide gene therapy with lentiviral vector.Protection of shrimp Penaeus monodon from WSSV infection using antisense constructs.HIV LTR-Driven Antisense RNA by Itself Has Regulatory Function and May Curtail Virus Reactivation From Latency.Autologous T-cell therapy based on a lentiviral vector expressing long antisense RNA targeted against HIV-1 env gene influences HIV replication and evolution in vivo.Antisense RNA: the new favorite in genetic research

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P2860

Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance

http://www.wikidata.org/entity/Q24564647

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2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004年の論文

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Antisense-mediated inhibition ...... pable of developing resistance

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JVI.78.13.7079-7088.2004

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Journal of Virology

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Antisense-mediated inhibition ...... pable of developing resistance

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P2093

Boro Dropulic

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Gwendolyn K Binder

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John Rossi

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Qiao Yu

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Tatiana Slepushkina

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Xiaobin Lu

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Ziping Chen

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P2860

Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons

Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

Inhibition of the human chemokine receptor CXCR4 by antisense phosphorothioate oligodeoxyribonucleotides.

Adverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV disease.

Search for the mechanism of genetic variation in the pro gene of human immunodeficiency virus.

Lipodystrophy syndrome in HIV infection: what is it, what causes it and how can it be managed?

Side effects of retroviral gene transfer into hematopoietic stem cells.

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7079-88

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1835363

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10.1128/JVI.78.13.7079-7088.2004

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13

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78

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15194784

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vector-borne disease

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421644

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